Beyond its critical function in calcium homeostasis, vitamin D has recently been found to
play an important role in the modulation of the immune/inflammation system via regulating …

Vitamin D is essential for calcium absorption and for maintaining bone health in the pediatric
population. Vitamin D deficiency may develop from nutritional deficiencies, malabsorption …

Pediatric cardiomyopathies, which are rare but serious disorders of the muscles of the heart,
affect at least one in every 100,000 children in the USA. Approximately 40% of children with …

Chronic kidney disease (CKD) is characterized by a loss of kidney function and
dysregulation of vitamin D metabolism. Well known are the defects in final activation of …

Results Seventy-two children were screened. Forty-seven children were 25 (OH) D-deficient
and randomly assigned to receive ergocalciferol or placebo. Twenty children in each arm …

Hypertension (HTN) and chronic kidney disease (CKD) are increasingly recognized in
pediatric patients and represent risk factors for cardiovascular morbidity and mortality later in …

Recent studies have provided evidence for an important role of vitamin D deficiency in the
pathogenesis of cardiovascular disease (CVD) in the general population, and of an …

Fibroblast growth factor 23 (FGF23) is a circulating protein that regulates the renal
reabsorption of phosphate and also inhibits 1-α-hydroxylase production. In adults FGF23 is …

Vitamin D deficiency is common in healthy adults and children as well as in the chronic
kidney disease (CKD) population. What was once a disease of malnourished children in the …

Background Vitamin D plays an important role in the mineral and bone disorder seen in
chronic kidney disease (CKD). Deficiency of 25-hydroxyvitamin D (25OHD) is highly …