Depression and the link with cardiovascular disease

AK Dhar, DA Barton - Frontiers in psychiatry, 2016 - frontiersin.org
This review provides an outline of the association between major depressive disorder
(MDD) and coronary heart disease (CHD). Much is known about the two individual clinical …

Roles of inflammation, oxidative stress, and vascular dysfunction in hypertension

QN Dinh, GR Drummond, CG Sobey… - BioMed research …, 2014 - Wiley Online Library
Hypertension is a complex condition and is the most common cardiovascular risk factor,
contributing to widespread morbidity and mortality. Approximately 90% of hypertension …

Gut dysbiosis is linked to hypertension

T Yang, MM Santisteban, V Rodriguez, E Li… - …, 2015 - Am Heart Assoc
Emerging evidence suggests that gut microbiota is critical in the maintenance of
physiological homeostasis. This study was designed to test the hypothesis that dysbiosis in …

Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions

J Ma, Y Li, X Yang, K Liu, X Zhang, X Zuo… - Signal transduction and …, 2023 - nature.com
Hypertension is a global public health issue and the leading cause of premature death in
humans. Despite more than a century of research, hypertension remains difficult to cure due …

Percutaneous renal denervation in patients with treatment-resistant hypertension: final 3-year report of the Symplicity HTN-1 study

H Krum, MP Schlaich, PA Sobotka, M Böhm, F Mahfoud… - The Lancet, 2014 - thelancet.com
Background Renal denervation (RDN) with radiofrequency ablation substantially reduces
blood pressure in patients with treatment-resistant hypertension. We assessed the long-term …

Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study

H Krum, M Schlaich, R Whitbourn, PA Sobotka… - The Lancet, 2009 - thelancet.com
Background Renal sympathetic hyperactivity is associated with hypertension and its
progression, chronic kidney disease, and heart failure. We did a proof-of-principle trial of …

Sympathetic nervous system overactivity and its role in the development of cardiovascular disease

SC Malpas - Physiological reviews, 2010 - journals.physiology.org
This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …

The sympathetic control of blood pressure

PG Guyenet - Nature Reviews Neuroscience, 2006 - nature.com
Hypertension—the chronic elevation of blood pressure—is a major human health problem.
In most cases, the root cause of the disease remains unknown, but there is mounting …

Renal sympathetic-nerve ablation for uncontrolled hypertension

MP Schlaich, PA Sobotka, H Krum… - … England Journal of …, 2009 - Mass Medical Soc
To the Editor: The renal sympathetic nerves have been identified as a major contributor to
the complex pathophysiology of hypertension in both experimental models and in humans. 1 …

Apparatus for performing a non-continuous circumferential treatment of a body lumen

D Demarais, H Gifford III, M Deem, N Zadno… - US Patent …, 2013 - Google Patents
Methods and apparatus are provided for non-continuous cir cumferential treatment of a body
lumen. Apparatus may be positioned within a body lumen of a patient and may deliver …