The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …

Astrocytes are morphologically complex, ubiquitous cells that are viewed as a
homogeneous population tiling the entire central nervous system (CNS). However, this view …

Primates and rodents, which descended from a common ancestor around 90 million years
ago, exhibit profound differences in behaviour and cognitive capacity; the cellular basis for …

The function of the mammalian brain relies upon the specification and spatial positioning of
diversely specialized cell types. Yet, the molecular identities of the cell types and their …

The assembly of cortical circuits involves the generation and migration of interneurons from
the ventral to the dorsal forebrain,–, which has been challenging to study at inaccessible …

Abstract Systems neuroscience seeks explanations for how the brain implements a wide
variety of perceptual, cognitive and motor tasks. Conversely, artificial intelligence attempts to …

In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …

The development of the nervous system involves a coordinated succession of events
including the migration of GABAergic (γ-aminobutyric-acid-releasing) neurons from ventral …

Neurons have diverse molecular, morphological, connectional and functional properties. We
believe that the only realistic way to manage this complexity—and thereby pave the way for …

Throughout development, the brain transits from early highly synchronous activity patterns to
a mature state with sparse and decorrelated neural activity, yet the mechanisms underlying …