[HTML][HTML] Evasion of host immune defenses by human papillomavirus
A majority of human papillomavirus (HPV) infections are asymptomatic and self-resolving in
the absence of medical interventions. Various innate and adaptive immune responses, as …
the absence of medical interventions. Various innate and adaptive immune responses, as …
Prevention and treatment of papillomavirus-related cancers through immunization
IH Frazer, GR Leggatt… - Annual review of …, 2011 - annualreviews.org
Cervical and other anogenital cancers are initiated by infection with one of a small group of
human papillomaviruses (HPV). Virus-like particle-based vaccines have recently been …
human papillomaviruses (HPV). Virus-like particle-based vaccines have recently been …
A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3
Purpose: To evaluate the safety and immunogenicity of a therapeutic human papillomavirus
(HPV) 16 DNA vaccine administered to women with HPV16+ cervical intraepithelial …
(HPV) 16 DNA vaccine administered to women with HPV16+ cervical intraepithelial …
[HTML][HTML] Modulation of antigen presenting cell functions during chronic HPV infection
High-risk human papillomaviruses (HR-HPV) infect basal keratinocytes, where in some
individuals they evade host immune responses and persist. Persistent HR-HPV infection of …
individuals they evade host immune responses and persist. Persistent HR-HPV infection of …
Development of therapeutic HPV vaccines
CL Trimble, IH Frazer - The lancet oncology, 2009 - thelancet.com
At least 15% of human malignant diseases are attributable to the consequences of
persistent viral or bacterial infection. Chronic infection with oncogenic human papillomavirus …
persistent viral or bacterial infection. Chronic infection with oncogenic human papillomavirus …
CXCR4 signaling controls dendritic cell location and activation at steady state and in inflammation
C Gallego, M Vétillard, J Calmette… - Blood, The Journal …, 2021 - ashpublications.org
Dendritic cells (DCs) encompass several cell subsets that collaborate to initiate and regulate
immune responses. Proper DC localization determines their function and requires the tightly …
immune responses. Proper DC localization determines their function and requires the tightly …
IL-17 suppresses immune effector functions in human papillomavirus-associated epithelial hyperplasia
Persistent infection with high-risk human papillomaviruses (HPV) causes epithelial
hyperplasia that can progress to cancer and is thought to depend on immunosuppressive …
hyperplasia that can progress to cancer and is thought to depend on immunosuppressive …
Nanomedicines modulating myeloid-derived suppressor cells for improving cancer immunotherapy
Great success in immunotherapy has revolutionized clinical cancer treatments. However, the
response rate and overall survival rate remain unsatisfactory. As one of the immunological …
response rate and overall survival rate remain unsatisfactory. As one of the immunological …
High-Risk Human Papillomavirus E7 Alters Host DNA Methylome and Represses HLA-E Expression in Human Keratinocytes
L Cicchini, RZ Blumhagen, JA Westrich, ME Myers… - Scientific reports, 2017 - nature.com
Human papillomavirus (HPV) infection distinctly alters methylation patterns in HPV-
associated cancer. We have recently reported that HPV E7-dependent promoter …
associated cancer. We have recently reported that HPV E7-dependent promoter …
Detection of human papillomavirus (HPV) 16-specific CD4+ T-cell immunity in patients with persistent HPV16-induced vulvar intraepithelial neoplasia in relation to …
MIE van Poelgeest, M van Seters, M van Beurden… - Clinical cancer …, 2005 - AACR
Purpose: Topical application of the immune response modifier imiquimod is an alternative
approach for the treatment of human papillomavirus (HPV)–positive vulvar intraepithelial …
approach for the treatment of human papillomavirus (HPV)–positive vulvar intraepithelial …