Progress in the management of ovarian granulosa cell tumor: A review

J Li, R Chu, Z Chen, J Meng, S Yao… - Acta obstetricia et …, 2021 - Wiley Online Library
Ovarian granulosa cell tumor (GCT) is a rare, low‐grade malignant tumor that accounts for
70% of the sex cord‐stromal tumors. It has two histopathologic types with different clinical …

Outcomes after fertility-sparing surgery for women with ovarian cancer: a systematic review of the literature

A Bercow, R Nitecki, PC Brady… - Journal of Minimally …, 2021 - Elsevier
Objective To compare reproductive and oncologic outcomes of patients diagnosed with
early-stage epithelial ovarian carcinoma, borderline ovarian tumors, or nonepithelial ovarian …

Mutant FOXL2C134W Hijacks SMAD4 and SMAD2/3 to Drive Adult Granulosa Cell Tumors

SE Weis-Banke, M Lerdrup, D Kleine-Kohlbrecher… - Cancer research, 2020 - AACR
The mutant protein FOXL2C134W is expressed in at least 95% of adult-type ovarian
granulosa cell tumors (AGCT) and is considered to be a driver of oncogenesis in this …

Adult granulosa cell tumors of the ovary: A retrospective study of 36 FIGO stage I cases with emphasis on prognostic pathohistological features

E Babarović, I Franin, M Klarić… - Analytical Cellular …, 2018 - Wiley Online Library
Objective. Adult granulosa cell tumors (AGCTs) represent 2%–5% of all ovarian
malignancies. The aim of this study was to analyze clinical and pathohistological parameters …

Conservative surgery in stage I adult type granulosa cells tumors of the ovary: Results from the MITO-9 study

A Bergamini, G Cormio, G Ferrandina, D Lorusso… - Gynecologic …, 2019 - Elsevier
Abstract Objective About 30% of Adult type granulosa cell tumors of the ovary (AGCTs) are
diagnosed in fertile age. In stage I, conservative surgery (fertility-sparing surgery, FSS) …

Analysis of oncologic and reproductive outcomes after fertility-sparing surgery in apparent stage I adult ovarian granulosa cell tumors

D Wang, D Cao, C Jia, H Huang, J Yang, M Wu… - Gynecologic …, 2018 - Elsevier
Objective We evaluated the oncological and reproductive outcomes after fertility-sparing
surgery (FSS) in patients with a stage I adult ovarian granulosa cell tumor (AGCT). Methods …

Fertility sparing surgery in sex-cord stromal tumors: oncological and reproductive outcomes

A Bergamini, FM Luisa, M Dellino, S Erica… - International Journal of …, 2022 - ijgc.bmj.com
Sex cord stromal tumors are rare neoplasms, frequently diagnosed in young women often as
early-stage disease. In patients who desire to preserve fertility, when possible, unilateral …

The prognostic significance of adjuvant chemotherapy in adult ovarian granulosa cell tumors: A systematic review and meta-analysis

Y Zhuang, H Yang - Cancer Control, 2023 - journals.sagepub.com
Introduction This study aimed to evaluate the oncological and prognostic significance of
adjuvant chemotherapy (CT) in patients with adult granulosa cell tumors of the ovary …

[HTML][HTML] Use of staging for sex cord stromal tumours

S Negri, T Grassi, R Fruscio - Current Opinion in Oncology, 2022 - journals.lww.com
Surgical staging should always be performed. It includes peritoneal samplings (peritoneal
washing, multiple peritoneal biopsies, omental biopsy and biopsy of any suspicious area) …

Is adjuvant chemotherapy beneficial for patients with FIGO stage IC adult granulosa cell tumor of the ovary?

D Wang, Y Xiang, M Wu, K Shen, J Yang… - Journal of Ovarian …, 2018 - Springer
Background To evaluate the association between adjuvant chemotherapy and clinical
outcomes in patients with stage IC adult granulosa cell tumor (AGCT). Methods We …