BACKGROUND Although the immune system intuitively must have an important role in
embryo implantation and in the achievement of a pregnancy, the molecular details have for …

COVID-19, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), has threatened public health worldwide. Host antiviral immune responses are …

The non-classical HLA-G is a well-known immune-modulatory molecule. In physiological
condition, HLA-G surface expression is restricted to the maternal–fetal interface and to …

Introduction A large number of risk and protective factors have been identified during the
SARS-CoV-2 pandemic which may influence the outcome of COVID-19. Among these …

Human leukocyte antigen (HLA)-G is a nonclassical MHC Class I molecule, which was
initially reported as a mediator of immune tolerance when expressed in extravillous …

HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents
substantial nucleotide variability in its regulatory regions. However, it encodes a limited …

Introduction Trophoblasts are essential in fetal-maternal interaction during pregnancy. The
goal was to study HLA profiles of primary trophoblasts derived from placentas, and to …

The human leukocyte antigen‐G (HLA‐G) is considered an immune checkpoint molecule
involved in tumor immune evasion. Hypoxia and the metabolic sensor hypoxia‐inducible …

The non-classical HLA class I molecule HLA-G is expressed in trophoblasts where it
contributes to maternal-fetal tolerance. HLA-G has been implicated in the control of …

Background Human leukocyte antigen G (HLA-G) is an immune checkpoint molecule with
relevance in several cancers. The aim of this study was to evaluate the potential role of …