Obesity and associated chronic inflammation were shown to facilitate breast cancer (BC)
growth and metastasis. Leptin, adiponectin, estrogen, and several pro-inflammatory …

Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Obesity and type 2 diabetes have both been associated with increased cancer risk and are
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …

The potential roles of breast cancer stem cells (BCSCs) in tumor initiation and recurrence
have been recognized for many decades. Due to their strong capacity for self-renewal and …

The rates of obesity and diabetes are increasing worldwide, whereas the age of onset for
both obesity and diabetes are decreasing steadily. Obesity and diabetes are associated with …

Obesity-related breast cancer is an important threat that affects especially post-menopausal
women. The link between obesity and breast cancer seems to be relying on the …

Insulin resistance (IR) is a condition which refers to individuals whose cells and tissues
become insensitive to the peptide hormone, insulin. Over the recent years, a wealth of data …

The escalating epidemic of overweight and obesity is currently recognized as one of the
most significant health and economic concern worldwide. At the present time, over 1.9 billion …

Breast cancer progression is highly dependent on the heterotypic interaction between tumor
cells and stromal cells of the tumor microenvironment. Cancer-associated adipocytes …

Simple Summary The involvement of leptin and adiponectin with receptors in the formation
of many types of cancer as well as their impact on the clinical course of cancer patients are …