Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Amino acid transporters (AATs) are membrane-bound transport proteins that mediate
transfer of amino acids into and out of cells or cellular organelles. AATs have diverse …

Astrocytes are housekeepers of the central nervous system (CNS) and are important for
CNS development, homeostasis and defence. They communicate with neurones and other …

Dopamine was first identified as a neurotransmitter localized to the midbrain over 50 years
ago. The dopamine transporter (DAT; SLC 6A3) and the vesicular monoamine transporter 2 …

Vesicular monoamine transporters (VMATs) are responsible for the packaging of
neurotransmitters such as dopamine, serotonin, norepinephrine, and epinephrine into …

Key points Excitatory and inhibitory interneurons of the spinal dorsal horn are critically
involved in normal sensory processing and in the generation of pathological pain, but their …

We report an approach to spatially resolve the content across nanometer neuroendocrine
vesicles in nerve-like cells by correlating super high-resolution mass spectrometry imaging …

Abstract Neuronal Ceroid Lipofuscinoses (NCLs), commonly known as Batten disease,
constitute a group of the most prevalent neurodegenerative lysosomal storage disorders …

The exocytotic release of neurotransmitters requires active transport into synaptic vesicles
and other types of secretory vesicles. Members of the SLC18 family perform this function for …

Amino acids are essential for cellular protein synthesis, growth, metabolism, signaling and in
stress responses. Cell plasma membranes harbor specialized transporters accumulating …