Role of natural stilbenes in the prevention of cancer

JA Sirerol, ML Rodríguez, S Mena… - Oxidative Medicine …, 2016 - Wiley Online Library
Natural stilbenes are an important group of nonflavonoid phytochemicals of polyphenolic
structure characterized by the presence of a 1, 2‐diphenylethylene nucleus. Stilbenes have …

New insights on COX-2 in chronic inflammation driving breast cancer growth and metastasis

HJ Hugo, C Saunders, RG Ramsay… - Journal of mammary …, 2015 - Springer
The medicinal use of aspirin stretches back to ancient times, before it was manufactured in
its pure form in the late 19th century. Its accepted mechanistic target, cyclooxygenase (COX) …

Curcumin and its nano-formulations: Defining triple-negative breast cancer targets through network pharmacology, molecular docking, and experimental verification

Z Deng, G Chen, Y Shi, Y Lin, J Ou, H Zhu… - Frontiers in …, 2022 - frontiersin.org
Background: Curcumin (CUR) displays the capability of suppressing the proliferation and
metastasis of various cancer cells. However, the effects and underline mechanisms of CUR …

EP4 as a therapeutic target for aggressive human breast cancer

M Majumder, P Nandi, A Omar, KC Ugwuagbo… - International journal of …, 2018 - mdpi.com
G-protein-coupled receptors (GPCRs, also called seven-transmembrane or heptahelical
receptors) are a superfamily of cell surface receptor proteins that bind to many extracellular …

Druggable molecular targets for the treatment of triple negative breast cancer

M Nakhjavani, JE Hardingham… - Journal of breast …, 2019 - synapse.koreamed.org
Breast cancer (BC) is still the most common cancer among women worldwide. Amongst the
subtypes of BC, triple negative breast cancer (TNBC) is characterized by deficient …

[HTML][HTML] Breast cancer cell cyclooxygenase-2 expression alters extracellular matrix structure and function and numbers of cancer associated fibroblasts

B Krishnamachary, I Stasinopoulos, S Kakkad… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Cyclooxygenase-2 (COX-2) is a critically important mediator of inflammation that
significantly influences tumor angiogenesis, invasion, and metastasis. We investigated the …

Regular and low-dose aspirin, other non-steroidal anti-inflammatory medications and prospective risk of HER2-defined breast cancer: the California Teachers Study

CA Clarke, AJ Canchola, LM Moy, SL Neuhausen… - Breast Cancer …, 2017 - Springer
Background Regular users of aspirin may have reduced risk of breast cancer. Few studies
have addressed whether risk reduction pertains to specific breast cancer subtypes defined …

Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling …

L Liu, J Yan, Y Cao, Y Yan, X Shen, B Yu… - Oncology …, 2021 - spandidos-publications.com
Breast cancer is the second most common cause of cancer‑associated mortality among
women worldwide, and triple negative breast cancer (TNBC) is the most aggressive subtype …

Prostaglandin E2 receptor 4 (EP4) as a therapeutic target to impede breast cancer-associated angiogenesis and lymphangiogenesis

GA De Paz Linares, RM Opperman, M Majumder… - Cancers, 2021 - mdpi.com
Simple Summary The formation of new blood (angiogenesis) and lymphatic
(lymphangiogenesis) vessels are major events associated with most epithelial …

Do olive and fish oils of the mediterranean diet have a role in triple negative breast cancer prevention and therapy? An exploration of evidence in cells and animal …

MG Donovan, OI Selmin, BJ Stillwater… - Frontiers in …, 2020 - frontiersin.org
Breast cancer is the most common malignancy and cause of cancer-related mortality among
women worldwide. Triple negative breast cancers (TNBC) are the most aggressive and …