NANOBODY®(a registered trademark of Ablynx NV) molecules (Nbs), also referred to as
single domain-based VHHs, are antibody fragments derived from heavy-chain only IgG …

Lateral flow assays (LFAs) are paper-based point-of-care (POC) diagnostic tools that are
widely used because of their low cost, ease of use, and rapid format. Unfortunately …

Unique, functional, homodimeric heavy chain–only antibodies, devoid of light chains, are
circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via …

The development of targeted medicine has greatly expanded treatment options and spurred
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …

A nanobody (Nb) is a registered trademark of Ablynx, referring to the single antigen‐binding
domain of heavy chain‐only antibodies (HCAbs) that are circulating in Camelidae. Nbs are …

Highlights•Nanobodies (Nbs) are camelid-derived single-domain antibodies.•Nbs have
powerful binding and inhibitory capacity with great therapeutic potential.•Nbs are used in …

Sera of camelids contain both conventional heterotetrameric antibodies and unique
functional heavy (H)-chain antibodies (HCAbs). The H chain of these homodimeric …

There is growing interest in using antibodies as auxiliary tools to crystallize proteins. Here
we describe a general protocol for the generation of Nanobodies to be used as …

Since the licensing of the first monoclonal antibody therapy in 1986, monoclonal antibodies
have become the largest class of biopharmaceuticals with over 80 antibodies currently …

From a home-based pregnancy self-testing kit, lateral flow assays (LFAs) have proliferated
and gained widespread utilization as point-of-care (POC) test kits. Their prevalence is due to …