Covering: up to February 2012 The complexity of terpenoid natural products has drawn
significant interest, particularly since their common (poly) isoprenyl origins were discovered …

Covering: up to the end of March 2010 Unlike the majority of terpenoids, a significant fraction
of the polycyclic diterpenoids (∼ 7000 already known) are now understood to originate from …

Background Terpenoids are among the most important constituents of grape flavour and
wine bouquet, and serve as useful metabolite markers in viticulture and enology. Based on …

The diterpenoids are classically defined by their composition—four isoprenyl units (20
carbons)—and are generally derived from [E, E, E]-geranylgeranyl diphosphate (GGPP) …

Tanshinones are abietane-type norditerpenoid quinone natural products that are the
bioactive components of the Chinese medicinal herb Salvia miltiorrhiza Bunge. The initial …

Plants produce thousands of diterpenoid natural products; some of which are of significant
industrial value as biobased pharmaceuticals (taxol), fragrances (sclareol), food additives …

Engineering biosynthetic pathways in heterologous microbial host organisms offers an
elegant approach to pathway elucidation via the incorporation of putative biosynthetic …

Biosynthetic gene clusters are common in microbial organisms, but rare in plants, raising
questions regarding the evolutionary forces that drive their assembly in multicellular …

The medicinal plant Salvia miltiorrhiza produces various tanshinone diterpenoids that have
pharmacological activities such as vasorelaxation against ischemia reperfusion injury and …

Plants produce over 10,000 different diterpenes of specialized (secondary) metabolism, and
fewer diterpenes of general (primary) metabolism. Specialized diterpenes may have …