Modified vaccinia virus Ankara: history, value in basic research, and current perspectives for vaccine development

A Volz, G Sutter - Advances in virus research, 2017 - Elsevier
Abstract Safety tested Modified Vaccinia virus Ankara (MVA) is licensed as third-generation
vaccine against smallpox and serves as a potent vector system for development of new …

The evolution of poxvirus vaccines

L Sánchez-Sampedro, B Perdiguero, E Mejías-Pérez… - Viruses, 2015 - mdpi.com
After Edward Jenner established human vaccination over 200 years ago, attenuated
poxviruses became key players to contain the deadliest virus of its own family: Variola virus …

Next generation vaccines and vectors: Designing downstream processes for recombinant protein‐based virus‐like particles

CL Effio, J Hubbuch - Biotechnology journal, 2015 - Wiley Online Library
In recent years, the development of novel recombinant virus‐like particles (VLPs) has been
generating new perspectives for the prevention of untreated and arising infectious diseases …

Recombinant modified vaccinia virus Ankara-based malaria vaccines

S Sebastian, SC Gilbert - Expert review of vaccines, 2016 - Taylor & Francis
A safe and effective malaria vaccine is a crucial part of the roadmap to malaria
elimination/eradication by the year 2050. Viral-vectored vaccines based on adenoviruses …

[图书][B] Viral nanotechnology

Y Khudyakov, P Pumpens - 2015 - books.google.com
This book presents a review of a rapidly developing field of viral nanotechnology in the
context of immunology, virology, microbiology, chemistry, physics, and mathematical …

Relevance of long-lived CD8+ T effector memory cells for protective immunity elicited by heterologous prime-boost vaccination

JR Vasconcelos, MR Dominguez, AF Araújo… - Frontiers in …, 2012 - frontiersin.org
Owing to the importance of major histocompatibility complex class Ia-restricted CD8+ T cells
for host survival following viral, bacterial, fungal, or parasitic infection, it has become largely …

Virus like particle comprising PD-1 antigen or PD-1 ligand antigen

W Akahata, R Ueno - US Patent 9,637,532, 2017 - Google Patents
Rodrigues M et al., Influenza and Vaccinia viruses expressing Malaria CD8+ T and B Cell
epitopes. Comparison of their immunogenicity and capacity to induce protective immunity, J …

Vaccination Using Recombinants Influenza and Adenoviruses Encoding Amastigote Surface Protein-2 Are Highly Effective on Protection against Trypanosoma cruzi …

RPA Barbosa, BG Filho, LI Santos, PAS Junior… - PLoS …, 2013 - journals.plos.org
In the present study we evaluated the protection raised by immunization with recombinant
influenza viruses carrying sequences coding for polypeptides corresponding to medial and …

猪细小病毒病毒样颗粒疫苗研究进展

刘运超, 陈玉梅, 姬鹏超, 赵宝磊, 王聚财, 邓瑞广… - 河南农业科学, 2015 - hnnykx.org.cn
猪细小病毒(PPV) 感染可导致母猪繁殖障碍, 断奶仔猪多系统衰弱综合征和肠炎性腹泻等疾病,
给养猪业造成巨大的经济损失. 临床防控以接种疫苗为主, 常用的疫苗有弱毒疫苗和灭活疫苗 …

Generation of porcine reproductive and respiratory syndrome (PRRS) virus-like-particles (VLPs) with different protein composition

MG Durán, S Costa, J Sarraseca, N de la Roja… - Journal of virological …, 2016 - Elsevier
The causative agent of Porcine Reproductive and Respiratory Syndrome (PRRS) is an
enveloped ssRNA (+) virus belonging to the Arteriviridae family. Gp5 and M proteins form …