ROS signaling cascades: dual regulations for osteoclast and osteoblast

H Tao, G Ge, X Liang, W Zhang, H Sun… - Acta Biochimica et …, 2020 - academic.oup.com
Accumulating evidence indicates that intracellular reactive oxygen species (ROS)
production is highly involved in bone homeostasis by intervening osteoclast or osteoblast …

Lycopene

AV Rao, MR Ray, LG Rao - Advances in food and nutrition research, 2006 - Elsevier
Oxidative stress is now recognized as an important etiological factor in the causation of
several chronic diseases including cancer, cardiovascular diseases, osteoporosis, and …

Scanning electrochemical microscopy

FRF Fan, B Liu, J Mauzeroll - Handbook of electrochemistry, 2007 - Elsevier
Publisher Summary The chapter discusses various techniques and applications of scanning
electrochemical microscopy (SECM), one of the scanning probe microscopies (SPM) in …

Parathyroid hormone secretion and action: evidence for discrete receptors for the carboxyl-terminal region and related biological actions of carboxyl-terminal ligands

TM Murray, LG Rao, P Divieti… - Endocrine reviews, 2005 - academic.oup.com
PTH is a major systemic regulator of the concentrations of calcium, phosphate, and active
vitamin D metabolites in blood and of cellular activity in bone. Intermittently administered …

Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats

S Muthusami, I Ramachandran, B Muthusamy… - Clinica chimica acta, 2005 - Elsevier
BACKGROUND: There is increasing evidence suggesting the role of free radicals in bone
resorption and bone loss. Ovariectomized rats have been used as the animal model for the …

Superoxide sensor based on cytochrome c immobilized on mixed-thiol SAM with a new calibration method

B Ge, F Lisdat - Analytica Chimica Acta, 2002 - Elsevier
Cytochrome c was immobilized on a mixed-thiol (mercaptoundecanoic acid/
mercaptoundecanol) modified gold electrode (MUA: MU/cyt c electrode). Characterization of …

Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics

L Qin, P Qiu, L Wang, X Li, JT Swarthout… - Journal of Biological …, 2003 - ASBMB
Parathyroid hormone (PTH) binds to its receptor PTH1R (parathyroid hormone 1 receptor) in
osteoblastic cells to regulate bone remodeling and calcium homeostasis. While prolonged …

Lycopene I—effect on osteoclasts: lycopene inhibits basal and parathyroid hormone-stimulated osteoclast formation and mineral resorption mediated by reactive …

LG Rao, N Krishnadev, K Banasikowska… - Journal of medicinal …, 2003 - liebertpub.com
Osteoclasts have been shown to produce reactive oxygen species (ROS) that can stimulate
bone resorption. We explored the hypothesis that lycopene, the antioxidant carotenoid from …

[HTML][HTML] Down-regulation of human osteoblast PTH/PTHrP receptor mRNA in end-stage renal failure

ML Picton, PR Moore, EB Mawer, D Houghton… - Kidney international, 2000 - Elsevier
Down-regulation of human osteoblast PTH/PTHrP receptor mRNA in end-stage renal failure.
Background Resistance to the action of parathyroid hormone (PTH) has been demonstrated …

Redox signaling and antioxidant defense in osteoclasts

H Tao, X Li, Q Wang, L Yu, P Yang, W Chen… - Free Radical Biology …, 2024 - Elsevier
Bone remodeling is essential for the repair and replacement of damaged or aging bones.
Continuous remodeling is necessary to prevent the accumulation of bone damage and to …