With the nucleus as an exception, mitochondria are the only animal cell organelles
containing their own genetic information, called mitochondrial DNA (mtDNA). During oocyte …

Mitochondria are essential organelles with specialized functions, which play crucial roles in
energy production, calcium homeostasis, and programmed cell death. In oocytes …

Reduced quality in oocytes from women of advanced maternal age (AMA) is associated with
dysfunctional mitochondria. The objective of this study was to investigate the mechanisms …

The female reproductive system is quite sensitive to regulation, and external environmental
stimuli may cause oxidative stress which in turn may lead to accelerated aging and …

Mitochondrial thermogenesis is an adaptive response of cells to their surrounding stress.
Oxidative stress is one of the common stresses during in vitro maturation (IVM) of oocytes …

The Mitochondria is a critical sub-cellular organelle that plays an integral part in a normal
cellular process. Besides ATP production, the mitochondria participate in various key …

In vitro generation of fertile oocytes has been reported in several mammalian species.
However, oocyte integrity is compromised by in vitro culture. Here, we aimed to understand …

Background Although hormonal and metabolic dysfunction have been recognized as a
possible cause of polycystic ovarian syndrome (PCOS), the associations between …

Oxidative stress caused by excess reactive oxygen species (ROS) is one of the main causes
of low efficiency in in vitro production of embryos. These ROS can cause mitochondrial …

Mitochondria have a crucial role in cellular function and exhibit remarkable plasticity,
adjusting both their structure and activity to meet the changing energy demands of a cell …