Streptococcus pneumoniae is a major cause of pneumonia, meningitis, and septicaemia
worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO …

Antibiotic resistance is a major global threat to the provision of safe and effective health care.
To control antibiotic resistance, vaccines have been proposed as an essential intervention …

Background Pneumococcal meningitis (PM) is a major invasive pneumococcal disease. Two
pneumococcal conjugate vaccines (PCVs) have been introduced in France: PCV7 was …

Infections caused by Streptococcus pneumoniae—including invasive pneumococcal
diseases (IPDs)—remain a significant public health concern worldwide. The marked winter …

Vaccines against bacterial pathogens can protect recipients from becoming infected with
potentially antibiotic-resistant pathogens. However, by altering the selective balance …

Measles, an acute viral disease, continues to be an important cause of childhood mortality
worldwide. Infection with the measles virus is thought to be associated with a transient but …

The seasonalities of influenza-like illnesses (ILIs) and invasive pneumococcal diseases
(IPDs) remain incompletely understood. Experimental evidence indicates that influenza …

Background. Infections by antibiotic-resistant Enterobacterales are a public health threat
worldwide. While dissemination of these opportunistic pathogens has been largely studied …

Abstract Purpose of Review This review summarizes major antimicrobial-resistant
pathogens emerging globally, including mechanisms of resistance and factors leading to …

Historically, every large-scale antibiotic use was followed by the emergence and selection of
resistant strains. This dogma was already true at the time of Fleming, since first description of …