Transcriptional memory is characterized by a primed cellular state, induced by an external
stimulus that results in an altered expression of primed genes upon re-exposure to the …

Transcriptional memory allows organisms to store information about transcriptional
reprogramming in response to a stimulus. In plants, this often involves the response to an …

Infectious diseases continue to claim many lives. Prevention of morbidity and mortality from
these diseases would benefit not just from new medicines and vaccines but also from a …

Developmental programming involves the accurate conversion of signalling levels and
dynamics to transcriptional outputs. The transcriptional relay in the Notch pathway relies on …

Highlights•Epigenetic transcriptional regulation allows for maintenance of stable expression
states.•Epigenetic regulation requires DNA methylation, lncRNAs or histone modifications.• …

Interferon-induced genes (ISG) are among the best-studied groups of coregulated genes.
Nevertheless, intense research into their regulation, supported by new technologies, is …

The largemouth bass is an economically important freshwater cultured fish species in China.
However, the rapid development of its aquaculture industry has been accompanied by …

Gamma-delta (γδ) T cells are a crucial component of the tumor immune microenvironment
which are considered a promising potential therapeutic strategy and target. Increasing …

Inflammation is a hallmark of remitting-relapsing dermatological diseases. While a large
emphasis has been placed on adaptive immune cells as mediators of relapse, evidence in …

Due to optimised treatment strategies and the availability of new therapies during the last
decades, formerly devastating chronic inflammatory diseases such as rheumatoid arthritis or …