Current status of mannose receptor-targeted drug delivery for improved anti-HIV therapy
In the pursuit of achieving better therapeutic outcomes in the treatment of HIV, innovative
drug delivery strategies have been extensively explored. Mannose receptors, which are …
drug delivery strategies have been extensively explored. Mannose receptors, which are …
Adipocyte-and monocyte-mediated vicious circle of inflammation and obesity (review of cellular and molecular mechanisms)
N Todosenko, O Khaziakhmatova… - International Journal of …, 2023 - mdpi.com
Monocytes play a key role in the development of metabolic syndrome, and especially
obesity. Given the complex features of their development from progenitor cells, whose …
obesity. Given the complex features of their development from progenitor cells, whose …
Impact of asialoglycoprotein receptor and mannose receptor deficiency on murine plasma N-glycome profiles
The asialoglycoprotein receptor (ASGPR) and the mannose receptor C-type 1 (MRC1) are
well known for their selective recognition and clearance of circulating glycoproteins …
well known for their selective recognition and clearance of circulating glycoproteins …
Mannose ligands for mannose receptor targeting
The mannose receptor (MR, CD 206) is an endocytic receptor primarily expressed by
macrophages and dendritic cells, which plays a critical role in both endocytosis and antigen …
macrophages and dendritic cells, which plays a critical role in both endocytosis and antigen …
Biological function, regulatory mechanism, and clinical application of mannose in cancer
H Jin, X Liu, H Liu - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Studies examining the regulatory roles and clinical applications of monosaccharides other
than glucose in cancer have been neglected. Mannose, a common type of monosaccharide …
than glucose in cancer have been neglected. Mannose, a common type of monosaccharide …
[HTML][HTML] Neutrophil aging exacerbates high fat diet induced metabolic alterations
Background High fat diet (HFD) chronically hyper-activates the myeloid cell precursors, but
whether it affects the neutrophil aging is unknown. Purpose We characterized how HFD …
whether it affects the neutrophil aging is unknown. Purpose We characterized how HFD …
Regional differences in the small intestinal proteome of control mice and of mice lacking lysosomal acid lipase
The metabolic contribution of the small intestine (SI) is still unclear despite recent studies
investigating the involvement of single cells in regional differences. Using untargeted …
investigating the involvement of single cells in regional differences. Using untargeted …
Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice
M Amor, V Bianco, M Buerger, M Lechleitner… - Cardiovascular …, 2023 - Springer
Abstract Background Matrix metalloproteinase 12 (MMP12) is a macrophage-secreted
protein that is massively upregulated as a pro-inflammatory factor in metabolic and vascular …
protein that is massively upregulated as a pro-inflammatory factor in metabolic and vascular …
ASGR1 deficiency diverts lipids toward adipose tissue but results in liver damage during obesity
Abstract Background Asialoglycoprotein receptor 1 (ASGR1), primarily expressed on
hepatocytes, promotes the clearance and the degradation of glycoproteins, including …
hepatocytes, promotes the clearance and the degradation of glycoproteins, including …
Angiotensin II type 1 receptor-associated protein in immune cells: a possible key factor in the pathogenesis of visceral obesity
S Tsukamoto, T Suzuki, H Wakui, T Uehara, J Ichikawa… - Metabolism, 2023 - Elsevier
Background and aim Dysregulation of angiotensin II type 1 receptor-associated protein
(ATRAP) expression in cardiovascular, kidney, and adipose tissues is involved in the …
(ATRAP) expression in cardiovascular, kidney, and adipose tissues is involved in the …