Large-scale mapping of mammalian transcriptomes identifies conserved genes associated with different cell states
Distinguishing cell states based only on gene expression data remains a challenging task.
This is true even for analyses within a species. In cross-species comparisons, the results …
This is true even for analyses within a species. In cross-species comparisons, the results …
The role of epigenetic mechanisms in lung diseases and environmental exposure
Many diseases result from complex interactions between genetics and the environment,
although the underlying mechanisms remain elusive. The epigenome acts as the interface …
although the underlying mechanisms remain elusive. The epigenome acts as the interface …
EpiAlign: an alignment-based bioinformatic tool for comparing chromatin state sequences
The availability of genome-wide epigenomic datasets enables in-depth studies of epigenetic
modifications and their relationships with chromatin structures and gene expression. Various …
modifications and their relationships with chromatin structures and gene expression. Various …
[图书][B] Statistical and Computational Methods for Comparing High-Throughput Data from Two Conditions
X Ge - 2021 - search.proquest.com
The development of high-throughput biological technologies have enabled researchers to
simultaneously perform analysis on thousands of features (eg, genes, genomic regions, and …
simultaneously perform analysis on thousands of features (eg, genes, genomic regions, and …
EpiAlign: an alignment-based bioinformatic tool for comparing chromatin state sequences
The availability of genome-wide epigenomic datasets enables in-depth studies of epigenetic
modifications and their relationships with chromatin structures and gene expression. Various …
modifications and their relationships with chromatin structures and gene expression. Various …
[HTML][HTML] Computational tool for visualization, analysis and comparison of epigenomes
OR Garcia - 2018 - dialnet.unirioja.es
Introducción El genoma eucariota contiene tanto información genética, codificada en la
secuencia de ADN, como instrucciones epigenéticas, que residen en factores asociados al …
secuencia de ADN, como instrucciones epigenéticas, que residen en factores asociados al …
Epigenetics and Epigenomic Studies in Asthma
H Ji - Genomic Approach to Asthma, 2018 - Springer
Over 235 million people worldwide suffer from asthma and it is the most common chronic
disease among children. As a reversible airway disease, asthma is very heterogeneous due …
disease among children. As a reversible airway disease, asthma is very heterogeneous due …
[图书][B] Systematic Identification and Analysis of Cell-state-associated cis-regulatory Elements Using Statistical Approaches
Y Yang - 2017 - search.proquest.com
Recent genome-wide studies have significantly advanced our understanding of the non-
coding genome in higher eukaryotes. Here we developed a novel computational method to …
coding genome in higher eukaryotes. Here we developed a novel computational method to …
Comprehensive mapping of mammalian transcriptomes identifies conserved genes associated with different cell differentiation states
Cell identity (or cell state) is established via gene expression programs, represented by
“associated genes” with dynamic expression across cell identities. Here we integrate RNA …
“associated genes” with dynamic expression across cell identities. Here we integrate RNA …