The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …

In today's modern era of medicine, macromolecular compounds such as proteins, peptides
and nucleic acids are dethroning small molecules as leading therapeutics. Given their …

Gene therapy represents a promising cancer treatment featuring high efficacy and limited
side effects, but it is stymied by a lack of safe and efficient gene-delivery vectors. Cationic …

Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

Nanomedicines employ multiple endocytic pathways to enter cells. Their following fate is
interesting, but it is not sufficient understood currently. This review introduces the endocytic …

Delivery of genes, including plasmid DNAs, short interfering RNAs (siRNAs), and
messenger RNAs (mRNAs), using artificial non-viral nanotherapeutics is a promising …

Antimicrobial peptides (AMPs) have been attracting much attention due to their excellent
antimicrobial efficiency and low rate in driving antimicrobial resistance (AMR), which has …

RNA interference is a phenomenon in which the introduction of double‐stranded RNA
(dsRNA) into cells triggers the degradation of the complementary messenger RNA in a …

After more than 20 years of intensive investigations, gene therapy has become one of the
most promising strategies for treating genetic diseases. However, the lack of ideal delivery …