Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

[HTML][HTML] Improving the study of brain-behavior relationships by revisiting basic assumptions

C Westlin, JE Theriault, Y Katsumi… - Trends in cognitive …, 2023 - cell.com
Neuroimaging research has been at the forefront of concerns regarding the failure of
experimental findings to replicate. In the study of brain-behavior relationships, past failures …

[HTML][HTML] Linking structure and function in macroscale brain networks

LE Suárez, RD Markello, RF Betzel, B Misic - Trends in cognitive sciences, 2020 - cell.com
Structure–function relationships are a fundamental principle of many naturally occurring
systems. However, network neuroscience research suggests that there is an imperfect link …

Schizophrenia—an overview

RA McCutcheon, TR Marques, OD Howes - JAMA psychiatry, 2020 - jamanetwork.com
Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical …

[HTML][HTML] The quest for multiscale brain modeling

E D'Angelo, V Jirsa - Trends in neurosciences, 2022 - cell.com
Addressing the multiscale organization of the brain, which is fundamental to the dynamic
repertoire of the organ, remains challenging. In principle, it should be possible to model …

Inversion of a large-scale circuit model reveals a cortical hierarchy in the dynamic resting human brain

P Wang, R Kong, X Kong, R Liégeois, C Orban… - Science …, 2019 - science.org
We considered a large-scale dynamical circuit model of human cerebral cortex with region-
specific microscale properties. The model was inverted using a stochastic optimization …

Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: recommendations of an expert panel

C Babiloni, X Arakaki, H Azami, K Bennys… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract The Electrophysiology Professional Interest Area (EPIA) and Global Brain
Consortium endorsed recommendations on candidate electroencephalography (EEG) …

[HTML][HTML] The scientific case for brain simulations

GT Einevoll, A Destexhe, M Diesmann, S Grün, V Jirsa… - Neuron, 2019 - cell.com
A key element of the European Union's Human Brain Project (HBP) and other large-scale
brain research projects is the simulation of large-scale model networks of neurons. Here, we …

[HTML][HTML] Concurrent TMS-fMRI for causal network perturbation and proof of target engagement

TO Bergmann, R Varatheeswaran, CA Hanlon… - Neuroimage, 2021 - Elsevier
The experimental manipulation of neural activity by neurostimulation techniques overcomes
the inherent limitations of correlative recordings, enabling the researcher to investigate …

Learning how network structure shapes decision-making for bio-inspired computing

M Schirner, G Deco, P Ritter - Nature Communications, 2023 - nature.com
To better understand how network structure shapes intelligent behavior, we developed a
learning algorithm that we used to build personalized brain network models for 650 Human …