Through annual epidemics and global pandemics, influenza A viruses (IAVs) remain a
significant threat to human health as the leading cause of severe respiratory disease. Within …

A limited arsenal of therapies is currently available to tackle the emergence of a future
influenza pandemic or even to deal effectively with the continual outbreaks of seasonal …

The advancement of viral glycomics has paralleled that of the mass spectrometry glycomics
toolbox. In some regard the glycoproteins studied have provided the impetus for this …

Hemagglutinins (HAs) are the receptor-binding and membrane fusion glycoproteins of
influenza viruses. They recognize sialic acid–containing, cell-surface glycoconjugates as …

In 2014, an outbreak of avian A/H10N7 influenza virus occurred among seals along North-
European coastal waters, significantly impacting seal populations. Here, we examine the …

Hemagglutinin (HA) is a transmembrane protein of the influenza A virus and a key
component in its life cycle. The protein allows the virus to enter a host cell by recognizing …

Ecological interactions between wild aquatic birds and outdoor-housed poultry can enhance
spillover events of avian influenza viruses (AIVs) from wild reservoirs to domestic birds, thus …

Influenza A viruses (IAV) initiate infection by binding to glycans with terminal sialic acids on
the cell surface. Hosts of IAV variably express two major forms of sialic acid, N …

Asparagine-linked N-glycans on proteins have diverse structures, and their functions vary
according to their structures. In recent years, it has become possible to obtain high quantities …

Of the eighteen hemagglutinin (HA) subtypes (H1–H18) that have been identified in bats
and aquatic birds, many HA subtypes have been structurally characterized. However …