Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

SC Cunnane, E Trushina, C Morland… - Nature reviews Drug …, 2020 - nature.com
The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

Nutritional interventions to support acute mTBI recovery

E Finnegan, E Daly, AJ Pearce, L Ryan - Frontiers in Nutrition, 2022 - frontiersin.org
When mild traumatic brain injury (mTBI) occurs following an impact on the head or body, the
brain is disrupted leading to a series of metabolic events that may alter the brain's ability to …

Lactate albumin ratio is associated with mortality in patients with moderate to severe traumatic brain injury

R Wang, M He, F Qu, J Zhang, J Xu - Frontiers in Neurology, 2022 - frontiersin.org
Background Traumatic brain injury (TBI) is a serious public health issue all over the world.
This study was designed to evaluate the prognostic value of lactate to albumin ratio (LAR) …

Fluid therapy in animals: physiologic principles and contemporary fluid resuscitation considerations

WW Muir, D Hughes, DC Silverstein - Frontiers in Veterinary Science, 2021 - frontiersin.org
What an oversight! Fluids are drugs (1), so why has one of the most administered, and
arguably beneficial, therapies employed in veterinary medicine been so inadequately …

Osmotherapy in patients with severe brain trauma: which agents should we take into account?

R Reina-Rivero, G Gaitán-Herrera… - Romanian …, 2022 - journals.lapub.co.uk
Traumatic brain injury is still a major cause of mortality and morbidity in the world and is
considered a public health problem that needs to be well attended to. Cerebral oedema due …

Fluid and Blood Management in Traumatic and Non-traumatic Surgical Emergencies

D Vanhonacker, M Mekeirele… - Textbook of Emergency …, 2023 - Springer
Most patients undergoing emergency surgery require fluid therapy to correct for fluid losses,
restore cardiac output, and therefore oxygen delivery. Fluids are drugs and should only be …

[HTML][HTML] Effects of Hypertonic Sodium Lactate on Intracranial Pressure in Patients With Traumatic Brain Injury: A Systematic Review and Meta-analysis on Clinical Trial …

R Mosaed, A Akhavan Rezayat, B Rohani… - Basic and Clinical …, 2024 - bcn.iums.ac.ir
Traumatic brain injury (TBI) is one of the most important causes of cerebral dysfunction, and
it is the reason for more than 30% of post-injury mortalities (Cassidy et al., 2004; Herbert et …

Neuroprotective Agents: A Simple Overview

A Sunjoyo, A Nugroho - Open Access Macedonian Journal of Medical …, 2022 - oamjms.eu
Neuroprotective agents are medications that can alter the course of metabolic events and
have neuroprotective function. Neuroprotective agents are needed in patients undergoing a …

Intracranial Hypertension in Intensive Care Unit

N Arora, CS Pingili - Procedures and Protocols in the Neurocritical Care …, 2022 - Springer
Abstract Management of Intracranial Hypertension in the Neurocritical care Unit (NCCU) is a
productive medical advancement. Neuro-intensivists and nursing staff should be aware of …

Decreased bioenergetics in traumatic brain injury

H Yost, M Quijas, H Smith, T Reed - Clinical Bioenergetics, 2021 - Elsevier
Abstract Annually, approximately 1.7 million individuals in the United States suffer from a
traumatic brain injury (TBI). This phenomenon is also a leading cause in two-thirds of injury …