Lysine's twofold action involves both mechanically flushing protein from proximal tubules to
shield the kidneys and initiating metabolic adaptations in the kidneys. This results in a net …

Unlike classical protein kinase A, with separate catalytic and regulatory subunits, EPACs are
single chain multi-domain proteins containing both catalytic and regulatory elements. The …

BACKGROUND: Hypertension or elevated blood pressure (BP) is a worldwide clinical
challenge and the leading primary risk factor for kidney dysfunctions, heart failure, and …

The inwardly rectifying K+ channel K ir 5.1 (Kcnj16) is essential in renal salt handling and
blood pressure control. However, the underlying mechanisms are not fully understood. Here …

Exercise training (Ex) has anti-hypertensive and renal protective effects. In this study, we
investigate the effects of Ex on mitochondrial fatty acid metabolism in the kidneys of Dahl salt …

Spatial metabolomics holds great promise for unraveling the complexities of metabolic
reprogramming in cancer, yet its development lags behind the rapid progress of spatial …

The first line of therapy for many cardiovascular and renal diseases is lifestyle changes that
involve low-salt diets. 1, 2 A lowsalt diet benefits renal function, particularly in people with …

Introduction: Investigating retinal biomarkers for Alzheimers disease (AD) and related
dementias (RD), has increased significantly. We examine retinal vascular health in a mouse …

Oxidative stress has been associated with the pathogenesis and progression of a diverse
range of human diseases, such as neurodegenerative, cardiovascular, and renal diseases …

Gynura procumbens merupakan tanaman dengan sifat diuretik yang telah digunakan
secara tradisional untuk mengobati batu ginjal. Kadar kalsium pada penelitian ini diperiksa …