Guidelines, Not Rules 14 Chemical Principles of Accessing Biomolecules in Expansion
Microscopy 14 Accessing Proteins 14 Protein Anchoring with Indirect Readout 14 Protein …

One of the biggest unsolved questions in neuroscience is how molecules and neuronal
circuitry create behaviors, and how their misregulation or dysfunction results in neurological …

Importance Factors associated with synapse loss beyond amyloid-β plaques and
neurofibrillary tangles may more closely correlate with the emergence of cognitive deficits in …

Resolving the distribution of specific proteins at the nanoscale in the ultrastructural context of
the cell is a major challenge in fluorescence microscopy. We report the discovery of a new …

Proteins are densely packed in cells and tissues, where they form complex nanostructures.
Expansion microscopy (ExM) variants have been used to separate proteins from each other …

Stimulated Raman scattering (SRS) microscopy is an emerging technology that provides
high chemical specificity for endogenous biomolecules and can circumvent common …

Expansion microscopy (ExM) improves imaging quality by physically enlarging the
biological specimens. In principle, combining a large expansion factor with optical super …

Observing cellular physiological histories is key to understanding normal and disease-
related processes. Here we describe expression recording islands—a fully genetically …

Long-term potentiation (LTP) is a cellular mechanism of learning and memory that results in
a sustained increase in the probability of vesicular release of neurotransmitter. However …

Spines are tiny nanoscale protrusions from dendrites of neurons. In the cortex and
hippocampus, most of the excitatory postsynaptic sites reside in spines. The bulbous spine …