METHODS A search for relevant articles was performed in PubMed and Scopus databases
to obtain the pooled relative risk (RR) and the corresponding 95% confidence intervals (CIs) …

Genome-wide association studies (GWAS) have been successful in deciphering the genetic
component of predisposition to many human complex diseases including prostate cancer …

Polygenic risk scores (PRS) have the potential to identify individuals at risk of diseases,
optimizing treatment, and predicting survival outcomes. Here, we construct and validate a …

Pharmacologically active natural products have played a significant role in the history of
drug development. They have acted as sources of therapeutic drugs for various diseases …

Soy isoflavone genistein (Gen) exerts beneficial effects against prostate cancer cells in vitro
and in vivo. However, its use as a chemoprevention/therapeutic agent is largely limited due …

The effects of different stocking densities on Litopenaeus vannamei were investigated from
the aspects of growth performance, immune response and transcriptome in this experiment …

Prostate cancer (PCa) is the second leading cause of cancer-related deaths in the United
States. The African (AA) descent has greater incidence and mortality rates of PCa as …

In the USA, Black men are approximately twice as likely to be diagnosed with and to die of
prostate cancer than white men. In the UK, despite Black men having vastly different …

Bay scallops are commercially important bivalve species for fisheries and aquaculture in
China, the USA, Peru and Chile, but their small size, short lifespan (< 14 months) and …

Objectives Genome-wide association studies have revealed over 200 genetic susceptibility
loci for prostate cancer (PCa). By combining them, polygenic risk scores (PRS) can be …