Personalized medicine has largely been enabled by the integration of genomic and other
data with electronic health records (EHRs) in the United States and elsewhere. Increased …

Clinical decision support (CDS) is an essential part of any pharmacogenomics (PGx)
implementation. Increasingly, institutions have implemented CDS tools in the clinical setting …

This chapter discusses information technology that provides health-care workers and
patients with situation-specific advice that can inform their decision making. The intricacies …

Background Machine learning–enabled clinical information systems (ML-CISs) have the
potential to drive health care delivery and research. The Fast Healthcare Interoperability …

Genomic knowledge is being translated into clinical care. To fully realize the value, it is
critical to place credible information in the hands of clinicians in time to support clinical …

Hereditary cancer syndromes result from germline genetic alterations predisposing
individuals to higher lifetime cancer risk than the general population. Hereditary cancer …

Objective Enabling clinicians to formulate individualized clinical management strategies
from the sea of molecular data remains a fundamentally important but daunting task. Here …

The successful implementation of pharmacogenetics (PGx) into clinical practice requires
patient genomic data to be shared between stakeholders in multiple settings. This creates a …

Background: Despite potential benefits, the practice of incorporating pharmacogenomics
(PGx) results in clinical decisions has yet to diffuse widely. In this study, we conducted a …

Objectives: To review the current state of research on designing and implementing clinical
decision support (CDS) using four current interoperability standards: Fast Healthcare …