Clinical challenges treating Stenotrophomonas maltophilia infections: an update

MF Mojica, R Humphries, JJ Lipuma… - JAC-antimicrobial …, 2022 - academic.oup.com
Stenotrophomonas maltophilia is a non-fermenting, Gram-negative bacillus that has
emerged as an opportunistic nosocomial pathogen. Its intrinsic multidrug resistance makes …

Stenotrophomonas maltophilia as an Emerging Ubiquitous Pathogen: Looking Beyond Contemporary Antibiotic Therapy

AA Adegoke, TA Stenström, AI Okoh - Frontiers in microbiology, 2017 - frontiersin.org
Stenotrophomonas maltophilia is a commensal and an emerging pathogen earlier noted in
broad-spectrum life threatening infections among the vulnerable, but more recently as a …

Mechanisms of antimicrobial resistance in Stenotrophomonas maltophilia: a review of current knowledge

T Gil-Gil, JL Martínez, P Blanco - Expert Review of Anti-infective …, 2020 - Taylor & Francis
Introduction: Stenotrophomonas maltophilia is a prototype of bacteria intrinsically resistant to
antibiotics. The reduced susceptibility of this microorganism to antimicrobials mainly relies …

Diversity and regulation of intrinsic β-lactamases from non-fermenting and other Gram-negative opportunistic pathogens

C Juan, G Torrens… - FEMS microbiology …, 2017 - academic.oup.com
This review deeply addresses for the first time the diversity, regulation and mechanisms
leading to mutational overexpression of intrinsic β-lactamases from non-fermenting and …

Novel marine metalloprotease—new approaches for inhibition of biofilm formation of Stenotrophomonas maltophilia

MK Peters, Y Astafyeva, Y Han, JFH Macdonald… - Applied Microbiology …, 2023 - Springer
Many marine organisms produce bioactive molecules with unique characteristics to survive
in their ecological niches. These enzymes can be applied in biotechnological processes and …

Resistance evolution can disrupt antibiotic exposure protection through competitive exclusion of the protective species

AM Quinn, MJ Bottery, H Thompson… - The ISME …, 2022 - academic.oup.com
Antibiotic degrading bacteria can reduce the efficacy of drug treatments by providing
antibiotic exposure protection to pathogens. While this has been demonstrated at the …

Treatment approaches for severe Stenotrophomonas maltophilia infections

MF Mojica, RA Bonomo, D Van Duin - Current Opinion in …, 2023 - journals.lww.com
Treatment approaches for severe Stenotrophomonas maltophilia... : Current Opinion in
Infectious Diseases Treatment approaches for severe Stenotrophomonas maltophilia infections …

Analysis of Phylogenetic Variation of Stenotrophomonas maltophilia Reveals Human-Specific Branches

J Steinmann, U Mamat, EM Abda, L Kirchhoff… - Frontiers in …, 2018 - frontiersin.org
Stenotrophomonas maltophilia is a non-fermenting Gram-negative bacterium that is
ubiquitous in the environment. In humans, this opportunistic multi-drug-resistant pathogen is …

Heterogeneous Colistin-Resistance Phenotypes Coexisting in Stenotrophomonas maltophilia Isolates Influence Colistin Susceptibility Testing

S Martínez-Servat, D Yero, P Huedo… - Frontiers in …, 2018 - frontiersin.org
The polymyxin antibiotic colistin shows in vitro activity against Stenotrophomonas
maltophilia. However, an increased incidence of colistin-resistant isolates has been recently …

Genetic Variants of the DSF Quorum Sensing System in Stenotrophomonas maltophilia Influence Virulence and Resistance Phenotypes Among Genotypically …

D Yero, P Huedo, O Conchillo-Solé… - Frontiers in …, 2020 - frontiersin.org
The pathogenicity of Stenotrophomonas maltophilia is regulated in part by its quorum
sensing (QS) system. The main QS signaling molecule in S. maltophilia is known as …