Autoimmune neuroinflammatory diseases: role of interleukins

AW Khan, M Farooq, MJ Hwang, M Haseeb… - International journal of …, 2023 - mdpi.com
Autoimmune neuroinflammatory diseases are a group of disorders resulting from abnormal
immune responses in the nervous system, causing inflammation and tissue damage. The …

Serum and cerebrospinal fluid biomarkers in neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein associated disease

A Dinoto, E Sechi, EP Flanagan, S Ferrari… - Frontiers in …, 2022 - frontiersin.org
The term neuromyelitis optica spectrum disorder (NMOSD) describes a group of clinical-MRI
syndromes characterized by longitudinally extensive transverse myelitis, optic neuritis …

Neuromyelitis optica spectrum disorder: from basic research to clinical perspectives

TL Huang, JK Wang, PY Chang, YR Hsu… - International Journal of …, 2022 - mdpi.com
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disease of the central
nervous system characterized by relapses and autoimmunity caused by antibodies against …

[HTML][HTML] T follicular helper cells contribute to pathophysiology in a model of neuromyelitis optica spectrum disorders

LW Yick, OKF Ma, EYY Chan, KX Yau, JSC Kwan… - JCI insight, 2023 - ncbi.nlm.nih.gov
Neuromyelitis optica spectrum disorders (NMOSD) are inflammatory autoimmune disorders
of the CNS. IgG autoantibodies targeting the aquaporin-4 water channel (AQP4-IgGs) are …

Proportions of Th17 cells and Th17-related cytokines in neuromyelitis optica spectrum disorders patients: a meta-analysis

MM Hou, YF Li, LL He, XQ Li, Y Zhang… - International …, 2019 - Elsevier
Background T helper (Th17) cells play an important role in many autoimmune diseases. In
this meta-analysis, we aimed to specify the proportion of Th17 cells and the levels of Th17 …

[HTML][HTML] Rituximab induces a transient fluctuation of peripheral and follicular helper T cells in neuromyelitis optica spectrum disorder

Z Huang, Y Liu, X An, C Zhang, TX Zhang, H Li… - Journal of …, 2023 - Elsevier
Autoreactive CD4+ helper T cells are implicated in the pathogenesis of neuromyelitis optica
spectrum disorder (NMOSD). Both PD-1+ CXCR5+ CD4+ T follicular helper (Tfh) cells and …

Interferon-γ controls aquaporin 4-specific Th17 and B cells in neuromyelitis optica spectrum disorder

G Arellano, E Loda, Y Chen, T Neef, AC Cogswell… - Brain, 2024 - academic.oup.com
Neuromyelitis optica spectrum disorder (NMOSD) is a CNS autoimmune inflammatory
disease mediated by T helper 17 (Th17) and antibody responses to the water channel …

The balance in T follicular helper cell subsets is altered in neuromyelitis optica spectrum disorder patients and restored by rituximab

P Nicolas, A Ruiz, A Cobo-Calvo, G Fiard… - Frontiers in …, 2019 - frontiersin.org
Neuromyelitis optica spectrum disorder (NMOSD) is a rare and severe auto-immune disease
of the central nervous system driven by pathogenic antibodies mainly directed against …

[HTML][HTML] Serum levels of IL-6 and IL-17 in multiple sclerosis, neuromyelitis optica patients and healthy subjects

F Ashtari, R Madanian, V Shaygannejad… - … journal of physiology …, 2019 - ncbi.nlm.nih.gov
Background: Studies reported that evaluating the interleukin serum level of MS and NMO
patients is helpful for differentiating these two diseases from each other. This study aimed to …

Aligning payer and provider strategies with the latest evidence to optimize clinical outcomes for patients with neuromyelitis optica spectrum disorder

DM Wingerchuk, BG Weinshenker… - Journal of managed …, 2022 - jmcp.org
BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune
disorder affecting the central nervous system that is associated with significant morbidity and …