Development and validation of a geometrically personalized finite element model of the lower ligamentous cervical spine for clinical applications

M Nikkhoo, CH Cheng, JL Wang, Z Khoz… - Computers in biology …, 2019 - Elsevier
Epidemiological and clinical studies show that the magnitude and scope of cervical disease
are on the rise, along with the world's rising aging population. From a biomechanical …

Comparative biomechanical analysis of rigid vs. flexible fixation devices for the lumbar spine: A geometrically patient-specific poroelastic finite element study

K Khalaf, M Nikkhoo - Computer methods and programs in biomedicine, 2021 - Elsevier
Abstract Background and Objective Lumbar spinal stenosis (LSS), or the narrowing of the
spinal canal, continues to be the leading preoperative diagnosis for adults older than 65 …

The influence of over-distraction on biomechanical response of cervical spine post anterior interbody fusion: A comprehensive finite element study

CH Cheng, PY Chiu, HB Chen, CC Niu… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: Anterior cervical discectomy and fusion (ACDF) has been considered as the
gold standard surgical treatment for cervical degenerative pathologies. Some surgeons tend …

Biomechanical investigation between rigid and semirigid posterolateral fixation during daily activities: geometrically parametric poroelastic finite element analyses

M Nikkhoo, ML Lu, WC Chen, CJ Fu, CC Niu… - … in bioengineering and …, 2021 - frontiersin.org
While spinal fusion using rigid rods remains the gold standard treatment modality for various
lumbar degenerative conditions, its adverse effects, including accelerated adjacent segment …

Biomechanical response of intact, degenerated and repaired intervertebral discs under impact loading–Ex-vivo and In-Silico investigation

M Nikkhoo, JL Wang, M Parnianpour, M El-Rich… - Journal of …, 2018 - Elsevier
Understanding the effect of impact loading on the mechanical response of the intervertebral
disc (IVD) is valuable for investigating injury mechanisms and devising effective therapeutic …

A meta-model analysis of a finite element simulation for defining poroelastic properties of intervertebral discs

M Nikkhoo, YC Hsu, M Haghpanahi… - Proceedings of the …, 2013 - journals.sagepub.com
Finite element analysis is an effective tool to evaluate the material properties of living tissue.
For an interactive optimization procedure, the finite element analysis usually needs many …

Biomechanical modeling of spinal ligaments: finite element analysis of L4-L5 spinal segment

S Hamidrad, M Abdollahi, V Badali… - Computer Methods in …, 2021 - Taylor & Francis
The complex mechanical structure of spine is usually simplified in finite element (FE) modes.
In this study, different 3D models of L4-L5 spinal segment distinguished by their ligament …

[HTML][HTML] Enzymatic denaturation versus excessive fatigue loading degeneration: Effects on the time-dependent response of the intervertebral disc

M Nikkhoo, JL Wang, CH Cheng, M Parnianpour… - Journal of …, 2024 - Elsevier
Degenerative disc disease (DDD), regardless of its phenotype and clinical grade, is widely
associated with low back pain (LBP), which remains the single leading cause of disability …

Creep experimental study on the lumbar intervertebral disk under vibration compression load

X Yang, X Cheng, Y Luan, Q Liu… - Proceedings of the …, 2019 - journals.sagepub.com
The intervertebral disk cushions the load generated by human activity and absorbs energy
to keep the spine moving steadily. Vibration condition is one of the important causes of disk …

A 3D finite element model updating of spinal lumber segment applying experimental modal data and particle swarm optimization algorithm

F Forouzesh, H Ahmadian… - Journal of Vibration …, 2023 - journals.sagepub.com
The dynamic loadings can be more harmful than static ones for the human lumbar spine
health. Consequently, the prediction of the spine behavior under dynamic and vibration …