Medical nanotechnology is surfacing as a challenging arena covering new biomedical applications, such as drug delivery, treatment, nano diagnosis, controlled drug release …
AI Miller, D Diaz, B Lin, PK Krzesaj, S Ustoyev, A Shim… - Biomedicines, 2023 - mdpi.com
The ketone bodies, sodium and lithium salts of acetoacetate (AcAc) and sodium 3- hydroxybutyrate (3-HB; commonly called beta-hydroxybutyrate) have been found to inhibit …
X Zhu, Z Shi, Y Mao, U Lächelt, R Huang - Small, 2024 - Wiley Online Library
Cell membrane is crucial for the cellular activities, and any disruption to it may affect the cells. It is demonstrated that cell membrane perforation is associated with some biological …
S Ben Abid, E Ketata, I Yacoubi, L Djemal… - PloS one, 2024 - journals.plos.org
P53 is a transcription factor that controls a variety of genes, primarily involved in cell cycle and other processes related to cell survival and death. We have isolated peptides targeting …
MR Pincus, B Lin, P Patel, E Gabutan, N Zohar… - Biomedicines, 2023 - mdpi.com
This is a review of approaches to the design of peptides and small molecules that selectively block the oncogenic RAS-p21 protein in ras-induced cancers. Single amino acid …
P Krzesaj, V Adler, RD Feinman… - Annals of Clinical & …, 2024 - Assoc Clin Scientists
Objective We have previously shown that the anti-cancer peptide PNC-27 kills cancer cells by co-localizing with membrane-expressed HDM-2, resulting in transmembrane pore …
V Alamdari-Palangi, KR Jaberi, M Shahverdi… - Journal of Cancer …, 2023 - Springer
Background Cancer, being a complex disease, presents a major challenge for the scientific and medical communities. Peptide therapeutics have played a significant role in different …
MR Pincus, M Silberstein, N Zohar, E Sarafraz-Yazdi… - Biomedicines, 2024 - mdpi.com
Recent advances in cancer treatment like personalized chemotherapy and immunotherapy are aimed at tumors that meet certain specifications. In this review, we describe a new …
P53 is a transcription factor that controls a variety of genes, primarily involved in cell cycle and other processes related to cell survival and death. We have isolated peptides targeting …