The immunomodulatory imide drug (IMiD) class, which includes the founding drug member
thalidomide and later generation drugs, lenalidomide and pomalidomide, has dramatically …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder that leads to
progressive cognitive decline and neuropathological changes. Pericytes, which are vessel …

This review article provides a comprehensive overview of thalidomide upper limb
embryopathy including updates about its pathogenesis, a historical account of the …

Background Although abnormal accumulation of amyloid beta (Aβ) protein is thought to be
the main cause of Alzheimer's disease (AD), emerging evidence suggests a pivotal vascular …

Background Over the past two decades, the field of radiation brain injury has attracted the
attention of an increasing number of brain scientists, particularly in the areas of molecular …

Background Accumulating evidence supports the involvement of adaptive immunity in the
development of radiation‐induced brain injury (RIBI). Our previous work has emphasized …

Background: Radiation exposure has been linked to the development of brain damage and
cognitive impairment, but the protective effect and mechanism of Lycium barbarum pills …

The neuron loss caused by the progressive damage to the nervous system is proposed to be
the main pathogenesis of neurodegenerative diseases. Ependyma is a layer of ciliated …

放射治疗后多聚ADP 核糖聚合酶-1 (PARP-1) 的过度激活与神经炎症反应密切相关,
而神经炎症是放射性认知功能障碍(RICD) 的主要发病机制. 该文分析了RICD …

Brain tumor patients are commonly treated with radiotherapy, but the efficacy of the
treatment is limited by its toxicity, particularly the risk of radionecrosis. We used human …