Mechanisms of Metal-Induced Hepatic Inflammation

NK Subramaniam, KK Mann - Current Environmental Health Reports, 2024 - Springer
Abstract Purpose of Review Worldwide, there is an increasing prevalence of hepatic
diseases. The most common diseases include alcoholic-associated liver disease (ALD) …

Arecoline-induced hepatotoxicity in rats: screening of abnormal metabolic markers and potential mechanisms

J Sun, K Zhang, Y Yin, Y Qi, S Li, H Sun, M Luo, Y Sun… - Toxics, 2023 - mdpi.com
Arecoline is a pyridine alkaloid derived from areca nut in the Arecaceae family. It has
extensive medicinal activity, such as analgesic, anti-inflammatory, and anti-allergic …

Nephroprotective effect of diosmin against sodium arsenite-induced renal toxicity is mediated via attenuation of oxidative stress and inflammation in mice

S Mohtadi, S Shariati, E Mansouri… - Pesticide Biochemistry and …, 2023 - Elsevier
Arsenic compounds, which are used in different industries like pesticide manufacturing,
cause severe toxic effects in almost all organs, including the kidneys. Since the primary …

Epicatechin ameliorates glucose intolerance and hepatotoxicity in sodium arsenite-treated mice

S Hejazi, M Moosavi, S Molavinia, E Mansouri… - Food and Chemical …, 2024 - Elsevier
Arsenic is a metalloid found in the environment that causes toxic effects in different organs,
mainly the liver. This study aimed to investigate the protective effects of epicatechin (EC), a …

Zingerone effects on arsenic-induced glucose intolerance and hepatotoxicity in mice via suppression of oxidative stress-mediated hepatic inflammation and apoptosis

M Hafezizadeh, M Salehcheh, S Mohtadi… - Journal of Trace …, 2024 - Elsevier
Abstract Background Arsenic (As), a poisonous metalloid, is widely distributed in air, water,
and soil and has been associated with the occurrence of diabetes and liver toxicity …

Hepatoprotective effects of zingerone on sodium arsenite-induced hepatotoxicity in rats: Modulating the levels of Caspase-3/Bax/Bcl-2, NLRP3/NF-κB/TNF-α and ATF6 …

B Eriten, C Caglayan, C Gür, S Küçükler… - … and Biophysical Research …, 2024 - Elsevier
Objective Long-term exposure to arsenic has been linked to several illnesses, including
hypertension, diabetes, hepatic and renal diseases and cardiovascular malfunction. The aim …

Antioxidant and anti-inflammatory potential of vanillic acid improves nephrotoxicity induced by sodium arsenite in mice

MJ Khodayar, M Shirani, S Shariati… - International Journal …, 2024 - Taylor & Francis
This study examined the potential of vanillic acid (VA) to protect against renal oxidative
stress and inflammation caused by sodium arsenite (SA) in mice. Mice were assigned to five …