Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges
Osteoarthritis (OA) has traditionally been defined as a prototypical non-inflammatory
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …
Metabolic syndrome meets osteoarthritis
QI Zhuo, W Yang, J Chen, Y Wang - Nature Reviews Rheumatology, 2012 - nature.com
Metabolic osteoarthritis (OA) has now been characterized as a subtype of OA, and links
have been discovered between this phenotype and metabolic syndrome (MetS)—both with …
have been discovered between this phenotype and metabolic syndrome (MetS)—both with …
[HTML][HTML] Clinical problems caused by obesity
I Kyrou, HS Randeva, C Tsigos, G Kaltsas… - 2015 - europepmc.org
4. Dr. Gregory Kaltsas MD FRCP (Lon) is a Professor in General Medicine and
Endocrinology at the National and Kapodistrian University of Athens, Greece. He was …
Endocrinology at the National and Kapodistrian University of Athens, Greece. He was …
Biomechanics, obesity, and osteoarthritis. The role of adipokines: When the levee breaks
V Francisco, T Pérez, J Pino, V López… - Journal of …, 2018 - Wiley Online Library
Osteoarthritis is a high‐incidence painful and debilitating disease characterized by
progressive degeneration of articular joints, which indicates a breakdown in joint …
progressive degeneration of articular joints, which indicates a breakdown in joint …
Obesity and pain
DS McVinnie - British journal of pain, 2013 - journals.sagepub.com
Recent reports suggest that almost half of the UK population is expected to be obese by
2030. A number of associations between obesity and chronic pain have been displayed in …
2030. A number of associations between obesity and chronic pain have been displayed in …
Regulation of subchondral bone osteoblast metabolism by cyclic compression
C Sanchez, L Pesesse, O Gabay… - Arthritis & …, 2012 - Wiley Online Library
Objective Recent data have shown that abnormal subchondral bone remodeling plays an
important role in osteoarthritis (OA) onset and progression, and it was suggested that …
important role in osteoarthritis (OA) onset and progression, and it was suggested that …
Non-pharmacological approaches for the treatment of osteoarthritis
F Rannou, S Poiraudeau - Best practice & research Clinical rheumatology, 2010 - Elsevier
For the most part, non-pharmacological approaches are recommended for osteoarthritis
treatment. This recommendation is based mainly on biomechanical observations leading to …
treatment. This recommendation is based mainly on biomechanical observations leading to …
Correlation of plasma and synovial fluid adiponectin with knee osteoarthritis severity
S Honsawek, M Chayanupatkul - Archives of medical research, 2010 - Elsevier
BACKGROUND AND AIMS: Osteoarthritis (OA) is a chronic degenerative joint disorder of
the synovial joint characterized by loss of articular cartilage, osteophyte formation, and …
the synovial joint characterized by loss of articular cartilage, osteophyte formation, and …
Long non-coding RNA HOTAIR promotes osteoarthritis progression via miR-17-5p/FUT2/β-catenin axis
J Hu, Z Wang, Y Shan, Y Pan, J Ma, L Jia - Cell death & disease, 2018 - nature.com
Osteoarthritis (OA) is a chronic joint disease and hard to cure at present. Accumulating
evidence suggests long noncoding RNA-HOTAIR (lncRNA-HOTAIR) plays important role in …
evidence suggests long noncoding RNA-HOTAIR (lncRNA-HOTAIR) plays important role in …
An extensive review regarding the adipokines in the pathogenesis and progression of osteoarthritis
C Tu, J He, B Wu, W Wang, Z Li - Cytokine, 2019 - Elsevier
Osteoarthritis is the most prevalent form of aging-related joint diseases, and its etiology is
still not fully understood. Obesity has been recognized as one of the most significant and …
still not fully understood. Obesity has been recognized as one of the most significant and …