Cancer across the tree of life: cooperation and cheating in multicellularity

CA Aktipis, AM Boddy, G Jansen… - … of the Royal …, 2015 - royalsocietypublishing.org
Multicellularity is characterized by cooperation among cells for the development,
maintenance and reproduction of the multicellular organism. Cancer can be viewed as …

The evolution of multicellularity: a minor major transition?

RK Grosberg, RR Strathmann - Annu. Rev. Ecol. Evol. Syst., 2007 - annualreviews.org
Benefits of increased size and functional specialization of cells have repeatedly promoted
the evolution of multicellular organisms from unicellular ancestors. Many requirements for …

Biological autonomy

A Moreno, M Mossio - A philo, 2015 - Springer
If we were to point out in a few words what characterises the phenomenon of life, we would
probably mention the amazing plasticity and robustness of living systems, the innumerable …

Orderly order in protein intrinsic disorder distribution: disorder in 3500 proteomes from viruses and the three domains of life

B Xue, AK Dunker, VN Uversky - Journal of Biomolecular Structure …, 2012 - Taylor & Francis
Intrinsically disordered proteins and intrinsically disordered protein regions are highly
abundant in nature. However, the quantitative and qualitative measures of protein intrinsic …

Signalling and differentiation in emulsion-based multi-compartmentalized in vitro gene circuits

A Dupin, FC Simmel - Nature chemistry, 2019 - nature.com
Multicellularity enables the growth of complex life forms as it allows for the specialization of
cell types, differentiation and large-scale spatial organization. In a similar way, modular …

Green algae as model organisms for biological fluid dynamics

RE Goldstein - Annual review of fluid mechanics, 2015 - annualreviews.org
In the past decade, the volvocine green algae, spanning from the unicellular
Chlamydomonas to multicellular Volvox, have emerged as model organisms for a number of …

Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity

EU Hammarlund, E Flashman, S Mohlin, F Licausi - Science, 2020 - science.org
BACKGROUND Animals and land plants are the most diverse complex multicellular life-
forms on Earth, and their success intricately links a capacity for adhering cells to perform …

[HTML][HTML] Promiscuity and specificity in BMP receptor activation

TD Mueller, J Nickel - FEBS letters, 2012 - Elsevier
Bone Morphogenetic Proteins (BMPs), together with Transforming Growth Factor (TGF)-β
and Activins/Inhibins constitute the TGF-β superfamily of ligands. This superfamily is formed …

A molecular timescale of eukaryote evolution and the rise of complex multicellular life

SB Hedges, JE Blair, ML Venturi, JL Shoe - BMC evolutionary biology, 2004 - Springer
Background The pattern and timing of the rise in complex multicellular life during Earth's
history has not been established. Great disparity persists between the pattern suggested by …

What is complexity?

C Adami - BioEssays, 2002 - Wiley Online Library
Arguments for or against a trend in the evolution of complexity are weakened by the lack of
an unambiguous definition of complexity. Such definitions abound for both dynamical …