[HTML][HTML] Multi-system inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection: review of clinical presentation, hypothetical pathogenesis, and …

NA Nakra, DA Blumberg, A Herrera-Guerra… - Children, 2020 - mdpi.com
Children | Free Full-Text | Multi-System Inflammatory Syndrome in Children (MIS-C)
Following SARS-CoV-2 Infection: Review of Clinical Presentation, Hypothetical …

The immunology of COVID-19: is immune modulation an option for treatment?

J Zhong, J Tang, C Ye, L Dong - The Lancet Rheumatology, 2020 - thelancet.com
In December, 2019, an outbreak of COVID-19 emerged in Wuhan, China and quickly spread
globally. As of May 7, 2020, there were 3 672 238 confirmed infections and 254 045 deaths …

[HTML][HTML] Management of adults and children receiving CAR T-cell therapy: 2021 best practice recommendations of the European Society for Blood and Marrow …

PJ Hayden, C Roddie, P Bader, GW Basak, H Bonig… - Annals of oncology, 2022 - Elsevier
Background Several commercial and academic autologous chimeric antigen receptor T-cell
(CAR-T) products targeting CD19 have been approved in Europe for relapsed/refractory B …

On the alert for cytokine storm: immunopathology in COVID‐19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
Poor outcomes in COVID‐19 correlate with clinical and laboratory features of cytokine storm
syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy …

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study

BJ Webb, ID Peltan, P Jensen, D Hoda… - The Lancet …, 2020 - thelancet.com
Background A subset of patients with COVID-19 develops a hyperinflammatory syndrome
that has similarities with other hyperinflammatory disorders. However, clinical criteria …

The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage …

B Shakoory, A Geerlinks, M Wilejto, K Kernan… - Annals of the rheumatic …, 2023 - Elsevier
Objective Haemophagocytic lymphohistiocytosis (HLH) and macrophage activation
syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes that can …

Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome

P Mehta, RQ Cron, J Hartwell, JJ Manson… - The Lancet …, 2020 - thelancet.com
The term cytokine storm syndromes describes conditions characterised by a life-threatening,
fulminant hypercytokinaemia with high mortality. Cytokine storm syndromes can be genetic …

Immunomodulatory therapy for the management of severe COVID-19. Beyond the anti-viral therapy: A comprehensive review

J Alijotas-Reig, E Esteve-Valverde, C Belizna… - Autoimmunity …, 2020 - Elsevier
Abstract Severe Acute Respiratory Syndrome related to Coronavirus-2 (SARS-CoV-2),
coronavirus disease-2019 (COVID-19) may cause severe illness in 20% of patients. This …

Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …