Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible of the
coronavirus disease 2019 (COVID-19) pandemic. Therapeutic options including …

More than 50 years have passed since Kawasaki disease (KD) was first reported. 1
According to a nationwide survey, the number of patients with KD who became adults was …

Neutrophils are best known for their critical role in host defense, for which they utilize
multiple innate immune mechanisms, including microbe-associated pattern recognition …

Kawasaki disease (KD) is a pediatric vasculitis with coronary artery aneurysms (CAA) as its
main complication. The diagnosis is based on the presence of persistent fever and clinical …

Soybeans are a rich source of isoflavones, which are classified as phytoestrogens. Despite
numerous proposed benefits, isoflavones are often classified as endocrine disruptors, based …

Intravenous IgG (IVIg) contains polyclonal immunoglobulin G (IgG) from thousands of
donors. It is administered at a low dose at regular intervals as antibody replacement therapy …

The introduction of intravenous immunoglobulin (IVIG) for modulation of inflammation in
acute Kawasaki disease was a great therapeutic triumph. However, three decades later, the …

The biological activities of human IgG antibodies predominantly rely on a family of receptors
for the Fc portion of IgG, FcγRs: FcγRI, FcγRIIA, FcγRIIB, FcγRIIC, FcγRIIIA, FcγRIIIB, FcRL5 …

Monoclonal antibodies (mAbs) are currently the largest and most dominant class of
therapeutic proteins. Inter-individual variability has been observed for several mAbs; …

Kawasaki disease, or mucocutaneous lymph node syndrome, most commonly affects
children between 6 months and 5 years of age. Approximately 90% of patients have …