Background The evidence for vitamin D and other agents that experimentally modulate T
regulatory cells (Tregs) for the treatment of patients with autoimmune or allergic diseases …

Cancer is generally regarded as a localised disease, with the well-established role of the
tumour microenvironment. However, the realm of cancer goes beyond the tumour …

Vitamin D (VD) is a fat-soluble prohormone well known for its role in regulating calcium and
phosphate metabolism. It has been clinically used for many years to prevent rickets in …

Molecular pathological epidemiology (MPE) is an integrative transdisciplinary field that
addresses heterogeneous effects of exogenous and endogenous factors (collectively …

Epidemiological studies have suggested inconclusive associations between 25-
hydroxyvitamin D and total cancer incidence and mortality. The aim of this study was to …

Women with low levels of vitamin D have a higher risk of developing breast cancer.
Numerous studies associated the presence of a CD8+ T cell infiltration with a good …

Melanoma is one of the most lethal types of skin cancer, with a poor prognosis once the
disease enters metastasis. The efficacy of currently available treatment schemes for …

Background Adipose tissue inflammation and fibrosis appear to contribute to insulin
resistance in obesity. Vitamin D receptor (Vdr) genes are expressed by adipocytes …

PURPOSE Vitamin D deficiency is described as a modifiable risk factor for the incidence of
and mortality in many common cancers; however, data in Hodgkin lymphoma (HL) are …

Several studies show that triple-negative breast cancer (TNBC) patients have the lowest
vitamin D concentration among all breast cancer types, suggesting that this vitamin may …