Lipid-associated GWAS loci as important markers of the risk, severity, and clinical course of peripheral artery disease

SN Zhabin, VA Lazarenko, IE Azarova… - Expert Review of …, 2024 - Taylor & Francis
Background This study investigated the relationship between lipid-associated loci identified
through genome-wide association studies (GWAS) and the risk of peripheral artery disease …

[HTML][HTML] A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment

C Gallego-Fabrega, G Temprano-Sagrera… - Journal of Thrombosis …, 2024 - Elsevier
Background Thrombolytic recombinant tissue plasminogen activator (r-tPA) treatment is the
only pharmacologic intervention available in the ischemic stroke acute phase. This treatment …

GWAS for the composite traits of hematuria and albuminuria

SA Gagliano Taliun, IR Dinsmore, T Mirshahi… - Scientific Reports, 2023 - nature.com
Our GWAS of hematuria in the UK Biobank identified 6 loci, some of which overlap with loci
for albuminuria suggesting pleiotropy. Since clinical syndromes are often defined by …

Risk of major vascular events in patients without traditional risk factors after transient ischemic attack or minor ischemic stroke: An international prospective cohort

S Uchiyama, T Hoshino, K Minematsu… - European Stroke …, 2024 - journals.sagepub.com
Introduction: To investigate the clinical characteristics in patients without traditional risk
factors (TRFs) after transient ischemic attack or minor ischemic stroke, who were recruited in …

Dissecting Complex Disease Pleiotropy Through Multi-Trait Association Studies

W Bone - 2023 - search.proquest.com
The success of biobanks in collecting phenotype and genotype data from millions of people
has dramatically changed the scale of genetic associations studies. The collection of these …