The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

Onset and frequency of depression in post-COVID-19 syndrome: A systematic review

O Renaud-Charest, LMW Lui, S Eskander… - Journal of psychiatric …, 2021 - Elsevier
Following recovery from COVID-19, an increasing proportion of individuals have reported
the persistence and/or new onset of symptoms which collectively have been identified as …

Predictors of COVID‐19 severity: a literature review

B Gallo Marin, G Aghagoli, K Lavine… - Reviews in medical …, 2021 - Wiley Online Library
Summary The coronavirus disease 2019 (COVID‐19) pandemic is a rapidly evolving global
emergency that continues to strain healthcare systems. Emerging research describes a …

Markers of immune activation and inflammation in individuals with postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection

MJ Peluso, S Lu, AF Tang… - The Journal of …, 2021 - academic.oup.com
Background The biological processes associated with postacute sequelae of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) are unknown. Methods …

Interleukin-6 is a biomarker for the development of fatal severe acute respiratory syndrome coronavirus 2 pneumonia

A Santa Cruz, A Mendes-Frias, AI Oliveira… - Frontiers in …, 2021 - frontiersin.org
Hyper-inflammatory responses induced by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are a major cause of disease severity and death. Predictive prognosis …

Gastrointestinal symptoms associated with COVID-19: impact on the gut microbiome

S Villapol - Translational Research, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the
greatest worldwide pandemic since the 1918 flu. The consequences of the coronavirus …

Could SARS-CoV-2 spike protein be responsible for long-COVID syndrome?

TC Theoharides - Molecular Neurobiology, 2022 - Springer
SARS-CoV-2 infects cells via its spike protein binding to its surface receptor on target cells
and results in acute symptoms involving especially the lungs known as COVID-19. However …

The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

V Carlini, DM Noonan, E Abdalalem, D Goletti… - Frontiers in …, 2023 - frontiersin.org
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity

V Legros, S Denolly, M Vogrig, B Boson… - Cellular & molecular …, 2021 - nature.com
Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of
protection against reinfection and, thus, for public health policy and vaccine development for …

A potential role of interleukin 10 in COVID-19 pathogenesis

L Lu, H Zhang, DJ Dauphars, YW He - Trends in Immunology, 2021 - cell.com
A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the
dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback …