This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

In Drosophila melanogaster, the causal links among a complex behaviour, single neurons
and single genes can be demonstrated through experimental manipulations. A key player in …

Genetic-based methods offer environmentally friendly species-specific approaches for
control of insect pests. One method, CRISPR homing gene drive that target genes essential …

Choosing a mate is one of the most consequential decisions a female will make during her
lifetime. A female fly signals her willingness to mate by opening her vaginal plates, allowing …

Exosomes are secreted nanovesicles with potent signalling activity that are initially formed
as intraluminal vesicles (ILVs) in late Rab7‐positive multivesicular endosomes, and also in …

The Drosophila ventral nerve cord (VNC) receives and processes descending signals from
the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory …

Neuronal information processing requires a large amount of energy, indicating that sugars
and other metabolites must be efficiently delivered. However, reliable neuronal function also …

Insects use taste to evaluate food, hosts, and mates. Drosophila has many" orphan" taste
neurons that express no known taste receptors. The Ionotropic Receptor (IR) superfamily is …

The courtship song of the Drosophila male serves as a genetically tractable model for the
investigation of the neural mechanisms of decision-making, action selection, and motor …

Principles of Neurobiology, Second Edition presents the major concepts of neuroscience
with an emphasis on how we know what we know. The text is organized around a series of …