Gamete development is a fundamental process that is highly conserved from early
eukaryotes to mammals. As germ cells develop, they must coordinate a dynamic series of …

The septate junction (SJ) provides an occluding function for epithelial tissues in invertebrate
organisms. This ability to seal the paracellular route between cells allows internal tissues to …

Migratory cells–either individually or in cohesive groups–are critical for spatiotemporally
regulated processes such as embryonic development and wound healing. Their …

Drosophila oogenesis requires the subsequent growth of distinct egg chambers each
containing a group of sixteen germline cells surrounded by a simple epithelium of follicle …

Septate junctions (SJs) evolved as cell-cell junctions that regulate the paracellular barrier
and integrity of epithelia in invertebrates. Multiple morphological variants of SJs exist …

Background Collective cell migration underlies many essential processes, including
sculpting organs during embryogenesis, wound healing in the adult, and metastasis of …

Simple Summary The eggshell that surrounds insect eggs acts as a barrier, protecting
against predators and desiccation. Despite its importance, how this intricate and …

Occluding junctions are essential for tissue integrity and barrier function in epithelial tissues.
Here we identify several non-occluding functions of septate junction components, the …

Migrating cell collectives are key to embryonic development but also contribute to invasion
and metastasis of a variety of cancers. Cell collectives can invade deep into tissues, leading …

Septate junction (SJ) proteins form an occluding barrier in invertebrate epithelium and are
functionally analogous to vertebrate tight junctions. Genetic studies in Drosophila have …