Blood-brain barrier disruption occurs in the early stages of Alzheimer's disease. Recent
studies indicate a link between blood-brain barrier dysfunction and cognitive decline and …

Neurological disorders have been linked to a defective blood–brain barrier (BBB), with
dysfunctions triggered by stage-specific disease mechanisms, some of these being …

Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Its
molecular mechanism is still unclear, and pharmacological treatments are unsatisfactory …

Background Neuroinflammation has recently emerged as a critical risk factor in the
pathophysiology of depression. However, the underlying molecular mechanisms and the …

Stringent transcriptional regulation is crucial for normal cellular biology and organismal
development. Perturbations in the proper regulation of transcription factors can result in …

Cerebrovascular disease is the most common life-threatening and debilitating condition that
often leads to stroke. The multifunctional calcium/calmodulin-dependent protein kinase II …

Aim Diabetes is a high-risk factor for neurocognitive dysfunction. Diabetic acute
hyperglycaemia accompanied by high osmotic pressure can induce immune cell …

Basal forebrain neurons increase cortical blood flow by releasing acetylcholine (Ach), which
stimulates endothelial cells (ECs) to produce the vasodilating gasotransmitter, nitric oxide …

Korean Red Ginseng (KRG) is an herbal medicine prescribed worldwide that is prepared
from Panax ginseng CA Meyer (Araliaceae). Out of ginseng's various components …

Background Exposure to carbon black nanoparticles (CBNPs), a well-known industrial
production, promotes pulmonary toxicity through inflammation and oxidative stress. Recent …