Monofluorination of organic compounds: 10 years of innovation

PA Champagne, J Desroches, JD Hamel… - Chemical …, 2015 - ACS Publications
Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …

Sulfur (VI) fluoride exchange (SuFEx): another good reaction for click chemistry

J Dong, L Krasnova, MG Finn… - Angewandte Chemie …, 2014 - Wiley Online Library
Aryl sulfonyl chlorides (eg Ts‐Cl) are beloved of organic chemists as the most commonly
used SVI electrophiles, and the parent sulfuryl chloride, O2SVICl2, has also been relied on …

Introduction of fluorine and fluorine‐containing functional groups

T Liang, CN Neumann, T Ritter - … Chemie International Edition, 2013 - Wiley Online Library
Over the past decade, the most significant, conceptual advances in the field of fluorination
were enabled most prominently by organo‐and transition‐metal catalysis. The most …

Modern carbon–fluorine bond forming reactions for aryl fluoride synthesis

MG Campbell, T Ritter - Chemical Reviews, 2015 - ACS Publications
In recent years, there has been a dramatic increase in available methods for the installation
of fluorine and fluorine-containing functional groups in organic molecules, 1− 4 and the …

Fluorine-18 radiochemistry, labeling strategies and synthetic routes

O Jacobson, DO Kiesewetter, X Chen - Bioconjugate chemistry, 2015 - ACS Publications
Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET)
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …

Synthesis of 11C, 18F, 15O, and 13N Radiolabels for Positron Emission Tomography

PW Miller, NJ Long, R Vilar… - Angewandte Chemie …, 2008 - Wiley Online Library
Positron emission tomography (PET) is a powerful and rapidly developing area of molecular
imaging that is used to study and visualize human physiology by the detection of positron …

Einführung von Fluor und fluorhaltigen funktionellen Gruppen

T Liang, CN Neumann, T Ritter - Angewandte Chemie, 2013 - Wiley Online Library
Die wichtigsten konzeptionellen Fortschritt auf dem Gebiet der Fluorierungen der letzten
zehn Jahre wurden durch die Organo‐und Übergangsmetallkatalyse ermöglicht. Die …

Chemistry with [18F]Fluoride Ion

L Cai, S Lu, VW Pike - European Journal of Organic Chemistry, 2008 - Wiley Online Library
The success of molecular imaging with positron‐emission tomography (PET) depends on
the availability of selective molecular probes labeled with positron‐emitters, such asfluorine …

A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry

HL Qin, Q Zheng, GAL Bare, P Wu… - Angewandte Chemie …, 2016 - Wiley Online Library
A Heck–Matsuda process for the synthesis of the otherwise difficult to access compounds, β‐
arylethenesulfonyl fluorides, is described. Ethenesulfonyl fluoride (ie, vinylsulfonyl fluoride …

Radiopharmaceutical chemistry for positron emission tomography

Z Li, PS Conti - Advanced drug delivery reviews, 2010 - Elsevier
Molecular imaging is an emerging technology that allows the visualization of interactions
between molecular probes and biological targets. Molecules that either direct or are subject …