Dynamic role of phospholipases A2 in health and diseases in the central nervous system

GY Sun, X Geng, T Teng, B Yang, MK Appenteng… - Cells, 2021 - mdpi.com
Phospholipids are major components in the lipid bilayer of cell membranes. These
molecules are comprised of two acyl or alkyl groups and different phospho-base groups …

[HTML][HTML] Inflammation and oxidative stress as mediators of the impacts of environmental exposures on human pregnancy: Evidence from oxylipins

BM Welch, EE McNell, ML Edin, KK Ferguson - Pharmacology & …, 2022 - Elsevier
Inflammation and oxidative stress play major roles in healthy and pathological pregnancy.
Environmental exposure to chemical pollutants may adversely affect maternal and fetal …

High sensitivity and wide linearity LC-MS/MS method for oxylipin quantification in multiple biological samples

X Fu, HH Yin, MJ Wu, X He, Q Jiang, LT Zhang… - Journal of Lipid …, 2022 - ASBMB
Oxylipins are important biological regulators that have received extensive research
attention. Due to the extremely low concentrations, large concentration variations, and high …

Prolonged experimental sleep disturbance affects the inflammatory resolution pathways in healthy humans

LC Engert, JM Mullington, M Haack - Brain, Behavior, and Immunity, 2023 - Elsevier
Background Sleep disturbances, as manifested in insomnia symptoms of difficulties falling
asleep or frequent nighttime awakenings, are a strong risk factor for a diverse range of …

Exploring foods as natural sources of FAHFAs—A review of occurrence, extraction, analytical techniques and emerging bioactive potential

TM Olajide, W Cao - Trends in Food Science & Technology, 2022 - Elsevier
Background Fatty acid esters of hydroxy fatty acids (FAHFAs) are a class of recently
discovered novel lipids gaining increasing attention due to their diverse biological roles …

Epoxides: an underestimated lipid oxidation product

KM Schaich - Free Radical Research, 2024 - Taylor & Francis
Immense gains in understanding of mechanisms and effects of lipid oxidation have been
achieved in the nearly 90 years over which lipid oxidation has been an active research …

Metabolomics meets lipidomics: Assessing the small molecule component of metabolism

H Gallart‐Ayala, T Teav, J Ivanisevic - BioEssays, 2020 - Wiley Online Library
Metabolomics, including lipidomics, is emerging as a quantitative biology approach for the
assessment of energy flow through metabolism and information flow through metabolic …

The role of oxylipins and their validation as biomarkers in the clinical context

SM Camunas-Alberca, M Moran-Garrido, J Sáiz… - TrAC Trends in …, 2023 - Elsevier
Oxylipins are bioactive lipid mediators that participate in a wide range of processes, from
blood flow to inflammation. In recent years, their exhaustive characterization as potential …

A MEPS-UHPLC-MS/MS analytical platform to detect isoprostanoids and specialized pro-resolving mediators in the urinary extracellular vesicles of mountain …

D Biagini, S Mrakic-Sposta, D Bondi, S Ghimenti… - Talanta, 2024 - Elsevier
Oxylipins are powerful signalling compounds derived from polyunsaturated fatty acids
(PUFAs) and involved in regulating the immune system response. A mass spectrometry …

Exploring oxylipins in processed foods: Understanding mechanisms, analytical perspectives, and enhancing quality with lipidomics

PW Harlina, V Maritha, X Yang, R Dixon, M Muchtaridi… - Heliyon, 2024 - cell.com
Oxylipins are active lipid compounds formed through the oxidation of unsaturated fatty acids.
These compounds have drawn considerable attention due to the potential impact on human …