Autoimmune diseases are pathological conditions that result from the misidentification of self-
antigens in immune system, leading to host tissue damage and destruction. These diseases …

Dynamic changes in gene expression are key factors in the development and activation of
immune cells. RNA metabolism is one of the critical steps for the control of gene expression …

Inflammatory response is a host-protective mechanism against tissue injury or infections, but
also has the potential to cause extensive immunopathology and tissue damage, as seen in …

Sterile inflammation either resolves the initial insult or leads to tissue damage. Kidney
ischemia/reperfusion injury (IRI) is associated with neutrophilic infiltration, enhanced …

Methamphetamine (METH) is a stimulant drug. METH abuse induces hepatotoxicity,
although the mechanisms are not well understood. METH-induced hepatotoxicity was …

Monocyte chemoattractant protein-induced protein 1 (MCPIP1), also called Regnase-1, is an
RNase that has been described as a key negative modulator of inflammation. MCPIP1 also …

Background The aim of this study was to evaluate oral bacteria‐and interleukin (IL)‐1β‐
induced protein and mRNA expression profiles of monocyte chemoattractant protein‐1 …

Sterile inflammation contributes to the development of many liver diseases including non-
alcoholic fatty liver disease. Tumor necrosis factor alpha (TNFα) is a key cytokine driving …

Lupus nephritis (LN) is a type of immunological complex glomerulonephritis characterized
by chronic renal inflammation which is exacerbated by infiltrating leukocytes and fueled by a …

Endotoxin tolerance is a state of hyporesponsiveness to LPS, triggered by previous
exposure to endotoxin. Such an immunosuppressive state enhances the risks of secondary …