A user-friendly approach is presented to sidestep the venerable Grignard addition to
unactivated ketones to access tertiary alcohols by reversing the polarity of the disconnection …

Conjugated ynones are easily accessible feedstock and the existence of an alkyne bond
endows ynones with different attractive reactivities, thus making them unique substrates for …

We report herein a regiodivergent and enantioselective allyl addition to ketones with
allenylsilanes through copper catalysis. With the combination of CuOAc, a Josiphos‐type …

Spirocyclic hexadienones with multiple stereogenic centers are frequently found in natural
products but remain challenging targets to synthesize. Herein, we report the …

Due to the wide applications of the resulting chiral tertiary homoallylic alcohols in organic
synthesis, catalytic asymmetric ketone allylations have attracted continuous attention from …

Pladienolides, an emerging class of naturally occurring spliceosome modulators, exhibit
interesting structural features, such as highly substituted 12-membered macrocycles and …

Iridium-tol-BINAP-catalyzed reductive coupling of allylic acetates with oxetanones and
azetidinones mediated by 2-propanol provides chiral α-stereogenic oxetanols and …

Herein, we report the development of a Cu-catalyzed aminoallylation of aldehyde
electrophiles through reductive coupling by circumventing the problematic competitive …

butanediol has attracted much attention and Lyondell method is a competitive production
technology due to its wide range of feedstock sources, in which the acetoxylation of …

Carbonyl allylation reactions constitute an important step in the formation of carbon–carbon
reactions, and involve various related reactions that chiefly use allylmetal reagents. This …