In high burden settings, the risk of infection with Mycobacterium tuberculosis increases
throughout childhood due to cumulative exposure. However, the risk of progressing from …

Our study investigated the circulating levels of factors involved in immune-inflammatory-
endocrine-metabolic responses in patients with tuberculosis with the aim of uncovering a …

Worldwide, around 14 million individuals are coinfected with both tuberculosis (TB) and
human immunodeficiency virus (HIV). In coinfected individuals, both pathogens weaken …

The nervous, endocrine and immune systems play a crucial role in maintaining homeostasis
and interact with each other for a successful defensive strategy against injurious agents …

Cell-mediated immunity, cytokines induced during the specific immune response and T-cell
populations are crucial factors for containing Mycobacterium tuberculosis infection. Recent …

We have analyzed the expression of glucocorticoid receptor (GR) isoforms by real time RT-
qPCR in PBMCs from 19 controls (HCo) and 28TB patients (8 mild; 12 moderate; 8 severe) …

Wasting is a prominent feature in tuberculosis (TB), but its underlying mechanisms are
incompletely understood. Immunoendocrine disturbances may be linked to the consumption …

Tuberculosis (TB) accounts for an increasing morbidity and mortality across the world.
Approximately 8.8 million new TB cases emerge and 1.6 million people die of this disease …

Background There is a high co-prevalence between type 2 diabetes (DM2) and other
infectious diseases. This is particularly problematic with the rise in co-prevalence between …

La tuberculosis (TB) es la primera causa de muerte en pacientes HIV+. La infección por
Mycobacterium tuberculosis induce la activación de células T CD8+, sin embargo, aún se …