Non‐absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic encephalopathy in people with …

LL Gluud, H Vilstrup… - Cochrane Database of …, 2016 - cochranelibrary.com
Background Non‐absorbable disaccharides (lactulose and lactitol) are recommended as
first‐line treatment for hepatic encephalopathy. The previous (second) version of this review …

[HTML][HTML] Gut-liver axis in liver cirrhosis: How to manage leaky gut and endotoxemia

H Fukui - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
A “leaky gut” may be the cutting edge for the passage of toxins, antigens or bacteria into the
body, and may play a pathogenic role in advanced liver cirrhosis and its complications …

[HTML][HTML] Rifaximin treatment in hepatic encephalopathy

NM Bass, KD Mullen, A Sanyal… - … England Journal of …, 2010 - Mass Medical Soc
Background Hepatic encephalopathy is a chronically debilitating complication of hepatic
cirrhosis. The efficacy of rifaximin, a minimally absorbed antibiotic, is well documented in the …

Comparison of rifaximin and lactitol in the treatment of acute hepatic encephalopathy: results of a randomized, double-blind, double-dummy, controlled clinical trial

A Mas, J Rodés, L Sunyer, L Rodrigo, R Planas… - Journal of …, 2003 - Elsevier
Background/Aims: The efficacy and safety of rifaximin in comparison with lactitol in the
treatment of acute hepatic encephalopathy was assessed in a prospective randomized …

Potential mechanisms of action of rifaximin in the management of hepatic encephalopathy and other complications of cirrhosis

JS Bajaj - Alimentary pharmacology & therapeutics, 2016 - Wiley Online Library
Background Progressive gut milieu (microbiota) changes occur in patients with cirrhosis and
are associated with complications [eg hepatic encephalopathy (HE)]. Aim To examine the …

Rifaximin: a review of its antibacterial activity, pharmacokinetic properties and therapeutic potential in conditions mediated by gastrointestinal bacteria

JC Gillis, RN Brogden - Drugs, 1995 - Springer
Synopsis Rifaximin is a derivative of rifamycin which acts by inhibiting bacterial ribonucleic
acid (RNA) synthesis. It is virtually unabsorbed after oral administration; thus it is used …

Efficacy of rifaximin in the treatment of symptomatic diverticular disease of the colon. A multicentre double‐blind placebo‐controlled trial

C Papi, A Ciaco, M Koch… - Alimentary pharmacology …, 1995 - Wiley Online Library
Background and aims: In a recent open trial we have shown the efficacy of long term
intermittent administration of a poorly absorbable antibiotic (rifaximin) in obtaining …

[HTML][HTML] Comparison of rifaximin and lactulose for the treatment of hepatic encephalopathy: a prospective randomized study

YH Paik, KS Lee, KH Han, KH Song, MH Kim… - Yonsei medical …, 2005 - ncbi.nlm.nih.gov
Rifaximin has been reported to be effective for the treatment of hepatic encephalopathy (HE)
in Europe. However, it is unknown whether Rifaximin is effective for the treatment of HE in …

Double-blind, double-dummy comparison between treatment andwith rifaximin and lactulose in patients with medium to severe patients with medium to severe

L Bucci, GC Palmieri - Current medical research and opinion, 1993 - Taylor & Francis
Fifty-eight patients, 30 males and 28 females, aged between 42 and 60 years I mean age 57
years) suffering from cirrhosis of the liver with signs and symptoms of portosystemic …

Mechanistic insight, diagnosis, and treatment of ammonia‐induced hepatic encephalopathy

SS Fiati Kenston, X Song, Z Li… - … of Gastroenterology and …, 2019 - Wiley Online Library
Hepatic encephalopathy is a neuropsychological syndrome due to biochemical disturbance
of brain function in advanced liver disease patients. Diagnosis and treatment of the condition …