Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review

S Uyttebroek, B Chen, J Onsea… - The Lancet Infectious …, 2022 - thelancet.com
According to the latest reports from WHO, the incidence of antibiotic-resistant bacterial
infections is increasing worldwide, resulting in increased morbidity and mortality and a rising …

Considerations for the use of phage therapy in clinical practice

GA Suh, TP Lodise, PD Tamma… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …

[HTML][HTML] Phage therapy in the resistance era: where do we stand and where are we going?

T Luong, AC Salabarria, DR Roach - Clinical therapeutics, 2020 - Elsevier
Purpose Widespread antibiotic-resistant bacteria are threatening the arsenal of existing
antibiotics. Not only are antibiotics less likely to be effective today, but their extensive use …

Phage cocktail development for bacteriophage therapy: toward improving spectrum of activity breadth and depth

ST Abedon, KM Danis-Wlodarczyk, DJ Wozniak - Pharmaceuticals, 2021 - mdpi.com
Phage therapy is the use of bacterial viruses as antibacterial agents. A primary
consideration for commercial development of phages for phage therapy is the number of …

Clinical Impact of Staphylococcus aureus Skin and Soft Tissue Infections

MS Linz, A Mattappallil, D Finkel, D Parker - Antibiotics, 2023 - mdpi.com
The pathogenic bacterium Staphylococcus aureus is the most common pathogen isolated in
skin-and-soft-tissue infections (SSTIs) in the United States. Most S. aureus SSTIs are caused …

A review of the biomaterials technologies for infection-resistant surfaces

D Campoccia, L Montanaro, CR Arciola - Biomaterials, 2013 - Elsevier
Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

Phage treatment of human infections

ST Abedon, SJ Kuhl, BG Blasdel, EM Kutter - Bacteriophage, 2011 - Taylor & Francis
Phages as bactericidal agents have been employed for 90 years as a means of treating
bacterial infections in humans as well as other species, a process known as phage therapy …

Current state of compassionate phage therapy

S McCallin, JC Sacher, J Zheng, BK Chan - Viruses, 2019 - mdpi.com
There is a current unmet medical need for the treatment of antibiotic-resistant infections, and
in the absence of approved alternatives, some clinicians are turning to empirical ones, such …

Phage therapy in clinical practice: treatment of human infections

E Kutter, D De Vos, G Gvasalia… - Current …, 2010 - ingentaconnect.com
Phage therapy is the application of bacteria-specific viruses with the goal of reducing or
eliminating pathogenic or nuisance bacteria. While phage therapy has become a broadly …

Nanotechnology: intelligent design to treat complex disease

P Couvreur, C Vauthier - Pharmaceutical research, 2006 - Springer
The purpose of this expert review is to discuss the impact of nanotechnology in the treatment
of the major health threats including cancer, infections, metabolic diseases, autoimmune …