Long non-coding RNAs in metabolic disorders: pathogenetic relevance and potential biomarkers and therapeutic targets

B Alipoor, S Nikouei, F Rezaeinejad… - Journal of …, 2021 - Springer
Background It has been suggested that dysregulation of long non-coding RNAs (lncRNAs)
could be associated with the incidence and development of metabolic disorders. Aim …

Long noncoding RNAs: novel important players in adipocyte lipid metabolism and derivative diseases

B Zhang, S Xu, J Liu, Y Xie, S Xiaobo - Frontiers in Physiology, 2021 - frontiersin.org
Obesity, a global public health issue, is characterized by excessive adiposity and is strongly
related to some chronic diseases including cardiovascular diseases and diabetes. Extra …

[HTML][HTML] MALAT1 polymorphisms and lung cancer susceptibility in a Chinese northeast han population

G Tong, W Tong, R He, Z Cui, S Li… - International journal of …, 2022 - ncbi.nlm.nih.gov
Background: LncRNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1)
was competitive endogenous RNA (ceRNA) involved in various molecular processes for …

Association of angio-LncRNAs MIAT rs1061540/MALAT1 rs3200401 molecular variants with gensini score in coronary artery disease patients undergoing …

MY Elwazir, MH Hussein, EA Toraih, E Al Ageeli… - Biomolecules, 2022 - mdpi.com
Long non-coding RNAs (lncRNAs) have emerged as essential biomolecules with variable
diagnostic and/or prognostic utility in several diseases, including coronary artery disease …

LncRNA MALAT1 promotes STAT3-mediated endothelial inflammation by counteracting the function of miR-590

Q Zhou, Q Run, CY Li, XY Xiong, XL Wu - Cytogenetic and genome …, 2020 - karger.com
The excessive production of inflammatory mediators by vascular endothelial cells (ECs)
greatly contributes to the development of atherosclerosis. In this study, we explored the …

LncRNA CASC11 was downregulated in coronary artery disease and inhibits transforming growth factor-β 1

J Chen, J Dang - Journal of International Medical Research, 2020 - journals.sagepub.com
Objective To investigate the involvement of long non-coding RNA (lncRNA) Cancer
Susceptibility 11 (CASC11) in patients with coronary artery disease (CAD). Methods This …

lncRNA‑MALAT1 expression in patients with coronary atherosclerosis and its predictive value for in‑stent restenosis

S Qiu, J Sun - Experimental and therapeutic medicine, 2020 - spandidos-publications.com
This study was designed to investigate the long non‑coding RNA (lncRNA)‑metastasis
associated lung adenocarcinoma transcript 1 (MALAT1) expression in patients with coronary …

Association of polymorphisms in MALAT1 with the risk of endometrial cancer in Southern Chinese women

G Chen, M Zhang, Z Liang, S Chen… - Journal of clinical …, 2020 - Wiley Online Library
Background Endometrial cancer is the most common gynecologic malignancy worldwide.
Polymorphisms in MALAT1 have been demonstrated to play critical roles in cancer …

The association between extracellular matrix metalloproteinase inducer polymorphisms and coronary heart disease: a potential way to predict disease

Y Weng, T Chen, J Ren, D Lu, X Liu, S Lin… - DNA and Cell …, 2020 - liebertpub.com
Extracellular matrix metalloproteinase inducer (EMMPRIN) had been reported to be involved
in the occurrence and development of coronary heart disease (CHD) in previous studies …

Potential Involvement of LncRNAs in Cardiometabolic Diseases

M Ilieva, S Uchida - Genes, 2023 - mdpi.com
Characterized by cardiovascular disease and diabetes, cardiometabolic diseases are a
major cause of mortality around the world. As such, there is an urgent need to understand …